Process Development in Antibiotic Fermentations

C. T. Calam

doi:10.1017/CBO9780511983702

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Process Development in Antibiotic Fermentations

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C. T. Calam

Publisher:: Cambridge University Press
Online publication date:: February 2012
Print publication year:: 1987
Online ISBN:: 9780511983702
DOI:: https://doi.org/10.1017/CBO9780511983702

Subjects:: Life Sciences, Microbiology and Immunology, Biotechnology
Series:: Cambridge Studies in Biotechnology (4)

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Process development in antibiotic fermentation is of microbiological and commercial importance and this book gives a consistent treatment of the area. It is divided into three parts: the first deals with the scientific background to the subject, the second with process development in the laboratory and the third with industrial fermentation plants and pilot plants. The discussion shows how problems change as processes are scaled up and yields increase. The book is written from a practical angle and examples of development work are given to support the background information. It will be particularly useful to students of applied microbiology and to those postgraduate microbiologists who are widening their experience with the development of antibiotic fermentations in relation to the production plant, both as a lecturer and as an industrial consultant and he has made use of his wide knowledge of all these areas in this book.

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Process Development in Antibiotic Fermentations

This Book has been cited by the following publications. This list is generated based on data provided by Crossref.

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Contents

Frontmatter
pp i-vi

Contents
pp vii-viii

Preface
pp ix-x

Part 1 - Background
pp 1-2

1 - Introduction
pp 3-8

2 - The microorganisms and methods of culture
pp 9-24

3 - Microbial Physiology
pp 25-48

4 - Microbial biochemistry
pp 49-56

5 - Subsidiary factors important in production fermentations
pp 57-64

6 - Submerged culture conditions: the interaction between environment and genotype
pp 65-74

Part 2 - Process development in the laboratory
pp 75-76

7 - Laboratory fermentation process development
pp 77-92

8 - Assessment and understanding of experimental results
pp 93-103

9 - Strain improvement
pp 104-117

10 - Methods for laboratory process development
pp 118-148

Part 3 - Industrial fermentation plants and pilot plants
pp 149-150

11 - Fermentation plants and pilot plants
pp 151-173

12 - Process development in the fermentation plant
pp 174-180

13 - Two plant problems: infection and variations in the level of production
pp 181-199

Postscript
pp 200-201

Bibliography
pp 202-202

References
pp 203-210

Index
pp 211-217

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Process Development in Antibiotic Fermentations

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