Skip to main content Accessibility help
×
Hostname: page-component-78c5997874-dh8gc Total loading time: 0 Render date: 2024-11-01T20:05:11.230Z Has data issue: false hasContentIssue false

Case 39 - A 25-Year-Old Woman Who Has Received a Letter from an Aunt Recommending Lynch Testing (Cascade Testing)

from Section VI - Cancer Screening and Prevention

Published online by Cambridge University Press:  20 February 2019

David Chelmow
Affiliation:
Virginia Commonwealth University
Nicole W. Karjane
Affiliation:
Virginia Commonwealth University
Hope A. Ricciotti
Affiliation:
Harvard Medical School
Amy E. Young
Affiliation:
University of Texas, Austin
Get access
Type
Chapter
Information
Office Gynecology
A Case-Based Approach
, pp. 118 - 121
Publisher: Cambridge University Press
Print publication year: 2019

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

American College of Obstetricians and Gynecologists. Lynch syndrome. Practice bulletin No. 147. Obstet Gynecol 2014;124:10421054.CrossRefGoogle Scholar
Barrow, E, Hill, J, Evans, DG. Cancer risk in Lynch syndrome. Fam Cancer 2013;12(2):229240.Google Scholar
Nakamura, K, Banno, K, Yanokura, M et al. Features of ovarian cancer in Lynch syndrome. Mol Clin Oncol. 2014;2(6):909916.Google Scholar
Lu, KH, Dinh, M, Kohlmann, W et al. Gynecologic cancer as a “sentinel cancer” for women with hereditary nonpolyposis colorectal cancer syndrome. Obstet Gynecol 2005;105:569574.Google Scholar
Vasen, H, Watson, P, Mecklin, JP, Lynch, H. New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative Group on HNPCC. Gastroenterology 1999;116(6):14531456.CrossRefGoogle Scholar
Umar, A, Boland, CR, Terdiman, JP et al. Revised Bethesda guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst 2004;96(4):261268.Google Scholar
National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology. Genetic/Familial High-Risk Assessment: Colorectal. Version 1.2017. Available at NCCN.org.Google Scholar
Lindor, NM, Petersen, GM, Hadley, DW et al. Recommendations for the care of individuals with an inherited predisposition to Lynch syndrome: a systematic review. JAMA 2006;296:15071517.Google Scholar
Burn, J, Gerdes, AM, Macrae, F et al. CAPP2 Investigators: long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial. Lancet 2011;378:20812087.Google Scholar
Schmeler, K, Lynch, HT, Chen, L et al. Prophylactic surgery to reduce the risk of gynecologic cancers in the Lynch Syndrome. N Engl J Med 2006;354:261269.CrossRefGoogle ScholarPubMed
Hampel, H. Genetic counseling and cascade genetic testing in Lynch syndrome. Fam Cancer 2016;15:423427.CrossRefGoogle ScholarPubMed
Stoffel, EM, Ford, B, Mercado, RC et al. Sharing genetic test results in Lynch syndrome: communication with close and distant relatives. Clin Gastroenterol Hepatol 2008;6(3):333338.CrossRefGoogle ScholarPubMed
American Medical Association, Code of Medical Ethics. Opinion E-2.131: Disclosure of Familial Risk in Genetic Testing. www.ama-assn.org/ama/pub/physician-resources/medical-ethics/code-medical-ethics/opinion2131.page. Accessed 11 January 2013.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×