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Chapter 2 - Evaluation of Candidates for Sperm Retrieval

from Part I - Introduction

Published online by Cambridge University Press:  09 April 2021

By
Darren J. Bryk ,
Neel V. Parekh  and
Sarah C. Vij
Edited by
Ashok Agarwal ,
Ahmad Majzoub  and
Sandro C. Esteves
Ashok Agarwal
Affiliation:
The Cleveland Clinic Foundation, Cleveland, OH, USA
Ahmad Majzoub
Affiliation:
Hamad Medical Corporation, Doha, Qatar
Sandro C. Esteves
Affiliation:
Andrology & Human Reproduction Clinic, Sao Paulo, Brazil
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Summary

There are a variety of management options for male infertility patients. Often, assisted reproductive technology allows for successful pregnancies and live births using an ejaculated semen sample. If the etiology of the infertility precludes a satisfactory ejaculated semen sample, sperm retrieval may be required. Determining if a patient is a candidate for sperm retrieval involves a thorough history and physical exam, semen analysis, endocrine evaluation and, likely, genetic assessment. Men who are candidates for sperm retrieval may be azoospermic or anejaculatory. Understanding the etiology of azoospermia is critical to determining the most effective sperm retrieval approach.

Keywords

sperm retrievalnonobstructive azoospermiaobstructive azoospermiasemen analysis
Type
Chapter
Information
Manual of Sperm Retrieval and Preparation in Human Assisted Reproduction , pp. 9 - 15
Publisher: Cambridge University Press
Print publication year: 2021

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References

Practice Committee of the American Society for Reproductive Medicine. Diagnostic evaluation of the infertile male: a committee opinion. Fertil Steril 2015;103:e18–e25.CrossRefGoogle Scholar
Chandra, A, Copen, CE, Stephen, EH. Infertility service use in the United States: data from the National Survey of Family Growth, 1982–2010. Natl Health Stat Report 2014;1–21. Available from: www.ncbi.nlm.nih.gov/pubmed/24467919.Google Scholar
Pastuszak, AW, Sigalos, JT, Lipshultz, LI. The role of the urologist in the era of in vitro fertilization-intracytoplasmic sperm injection. Urology 2017;103:19–26.CrossRefGoogle ScholarPubMed
Palermo, G, Joris, H, Devroey, P, Van Steirteghem, AC. Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte. Lancet 1992;340:17–18.CrossRefGoogle ScholarPubMed
Niederberger, CS. Male infertility. In Wein, AJ, Kavoussi, LR, Partin, AW, Peters, CA (eds.) Campbell Walsh Urol, 11th edn. Elsevier, Amsterdam, 2016, pp. 556–579.e1.Google Scholar
Katz, DJ, Teloken, P, Shoshany, O. Male infertility: the other side of the equation. Aust Fam Physician 2017;46:641–646.Google ScholarPubMed
Pan, MM, Hockenberry, MS, Kirby, EW, Lipshultz, LI. Male infertility diagnosis and treatment in the era of in vitro fertilization and intracytoplasmic sperm injection. Med Clin North Am 2018;102:337–347.CrossRefGoogle ScholarPubMed
Patel, ZP, Niederberger, CS. Male factor assessment in infertility. Med Clin North Am 2011;95:223–234.CrossRefGoogle ScholarPubMed
Anguiano, A, Oates, RD, Amos, JA, et al. Congenital bilateral absence of the vas deferens: a primarily genital form of cystic fibrosis. JAMA 1992;267:1794–1797.CrossRefGoogle ScholarPubMed
Choi, WS, Kim, SW. Current issues in varicocele management: a review. World J Mens Health 2013;31:12–20.Google Scholar
Cooper, TG, Noonan, E, Eckardstein, S et al. World Health Organization reference values for human semen characteristics. Hum Reprod Update 2010;16:231–245.CrossRefGoogle ScholarPubMed
Guzick, DS, Overstreet, JW, Factor-Litvak, P, et al. Sperm morphology, motility, and concentration in fertile and infertile men. N Engl J Med 2001;345:1388–1393.Google Scholar
Hwang, K, Smith, JF, Coward, RM, et al. Evaluation of the azoospermic male: a committee opinion. Fertil Steril 2018;109:777–782.Google Scholar
Shin, DH, Turek, PJ. Sperm retrieval techniques. Nat Rev Urol 2013;10:723–730.Google Scholar
Esteves, SC, Miyaoka, R, Agarwal, A. An update on the clinical assessment of the infertile male. Clinics (Sao Paulo) 2011;66:691–700.CrossRefGoogle ScholarPubMed
WHO. Laboratory Manual for the Examination and Processing of Human Semen, 5th edn., WHO, Geneva, 2010. Available from: https://apps.who.int/iris/bitstream/handle/10665/44261/9789241547789_eng.pdf;jsessionid=C7110716A3650EF69976E4C912ED8D19?sequence=1.Google Scholar
Agarwal, A, Majzoub, A, Esteves, SC, et al. Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios. Transl Androl Urol 2016;5:935–950.CrossRefGoogle ScholarPubMed
Hamada, A, Esteves, S, Agarwal, A. A comprehensive review of genetics and genetic testing in azoospermia. Clinics 2013;68:39–60.Google Scholar
Wosnitzer, M, Goldstein, M, Hardy, MP. Review of azoospermia. Spermatogenesis 2014;4:e28218.Google Scholar
Schoor, Ra, Elhanbly, S, Niederberger, CS, Ross, LS. The role of testicular biopsy in the modern management of male infertility. J Urol 2002;167:197–200.Google Scholar
Esteves, SC, Miyaoka, R, Roque, M, Agarwal, A. Outcome of varicocele repair in men with nonobstructive azoospermia: systematic review and meta-analysis. Asian J Androl 2016;18:246–253.Google Scholar
Practice Committee of the American Society for Reproductive Medicine. Management of nonobstructive azoospermia: a committee opinion. Fertil Steril 2018;110:1239–1245.CrossRefGoogle Scholar
Oates, RD. The natural history of endocrine function and spermatogenesis in Klinefelter syndrome: what the data show. Fertil Steril 2012;98:266–273.Google Scholar
Terribile, M, Stizzo, M, Manfredi, C, et al. 46,XX testicular disorder of sex development (DSD): a case report and systematic review. Medicina (B Aires) 2019;55:371.Google Scholar
Mehta, A, Sigman, M. Management of the dry ejaculate: a systematic review of aspermia and retrograde ejaculation. Fertil Steril 2015;104:1074–1081.CrossRefGoogle ScholarPubMed
Practice Committee of the American Society for Reproductive Medicine and The Society for Male Reproduction and Urology. The management of obstructive azoospermia: a committee opinion. Fertil Steril 2019 ; 111 :873–880.Google Scholar
Tournaye, H. Male factor infertility and ART. Asian J Androl 2012;14:103–108.CrossRefGoogle ScholarPubMed
Esteves, SC, Roque, M, Bradley, CK, Garrido, N. Reproductive outcomes of testicular versus ejaculated sperm for intracytoplasmic sperm injection among men with high levels of DNA fragmentation in semen: systematic review and meta-analysis. Fertil Steril 2017;108:456–467.e1.Google Scholar
Van Peperstraten, AM, Proctor, ML, Johnson, NP, Philipson, G. Techniques for surgical retrieval of sperm prior to intracytoplasmic sperm injection (ICSI) for azoospermia. Cochrane Database Syst Rev 2008;16:CD002807.Google Scholar
Donoso, P, Tournaye, H, Devroey, P. Which is the best sperm retrieval technique for non-obstructive azoospermia? A systematic review. Hum Reprod Update 2007;13:539–549.Google Scholar

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