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Chapter 34 - Central nervous system pharmacology

from Section 3 - Pharmacology

Published online by Cambridge University Press:  19 January 2017

By
Tim Smith
Edited by
Ted Lin ,
Tim Smith  and
Colin Pinnock
Edited in association with
Chris Mowatt
Ted Lin
Affiliation:
Glenfield Hospital, Leicester
Tim Smith
Affiliation:
Alexandra Hospital, Redditch
Colin Pinnock
Affiliation:
Alexandra Hospital, Redditch
Chris Mowatt
Affiliation:
Royal Shrewsbury Hospital
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Summary

Many drugs act on the central nervous system (CNS), with various specific aims in mind. While certain categories of drugs are considered elsewhere (anaesthetic gases and vapours in Chapter 29, hypnotics and intravenous agents in Chapter 30), other drugs acting on the CNS have been grouped here. Antiemetic drugs are considered in detail, with specific pharmacology of individual agents to reflect their direct relevance to the practice of anaesthesia.

Type
Chapter
Information
Fundamentals of Anaesthesia , pp. 667 - 679
Publisher: Cambridge University Press
Print publication year: 2016

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References

References and further reading

Diemunsch, P, Schoeffler, P, Bryssine, B, et al. Antiemetic activity of the NK1 receptor antagonist GR205171 in the treatment of postoperative nausea and vomiting after major gynaecological surgery. Br J Anaesth 1999; 82: 274–6.CrossRefGoogle ScholarPubMed
Gan, TJ. Risk factors for postoperative nausea and vomiting. Anesth Analg 2006; 102: 1884–98.CrossRefGoogle ScholarPubMed
Taylor, CP, Gee, NS, Su, T, et al. A summary of mechanistic hypotheses of gabapentin pharmacology. Epilepsy Res 1998; 29: 233–49.CrossRefGoogle ScholarPubMed
Vasudev, A, MacRitchie, K, Rao, SNK, Geddes, JR, Young, AH. Tiagabine in the treatment of acute affective episodes in bipolar disorder: efficacy and acceptability. Cochrane Database Syst Rev 2006; (3): CD004694.CrossRefGoogle Scholar
Williams, PI, Smith, M. An assessment of prochlorperazine buccal for the prevention of nausea and vomiting during intravenous patient-controlled analgesia with morphine following abdominal hysterectomy. Eur J Anaesthesiol 1999; 16: 638–45.CrossRefGoogle ScholarPubMed

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