Cognitive Impairment in Major Depressive Disorder: Clinical Relevance, Biological Substrates, and Treatment Opportunities

Danielle S. Cha

doi:10.1017/CBO9781139860567

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Cognitive Impairment in Major Depressive Disorder

Cognitive Impairment in Major Depressive Disorder

Clinical Relevance, Biological Substrates, and Treatment Opportunities

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Pan, Zihang Park, Caroline Brietzke, Elisa Zuckerman, Hannah Rong, Carola Mansur, Rodrigo B. Fus, Dominika Subramaniapillai, Mehala Lee, Yena and McIntyre, Roger S. 2019. Cognitive impairment in major depressive disorder. CNS Spectrums, Vol. 24, Issue. 1, p. 22.

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Edited by Roger S. McIntyre, University of Toronto
Edited in association with Danielle S. Cha, University of Toronto

Publisher: Cambridge University Press
Online publication date: March 2016
Print publication year: 2016
Online ISBN: 9781139860567
DOI: https://doi.org/10.1017/CBO9781139860567

Subjects: Neuropsychology, Psychiatry and Clinical Psychology, Medicine, Psychiatry

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Cognitive Impairment in Major Depressive Disorder
Edited by Roger S. McIntyre

Edited in association with Danielle S. Cha
Online ISBN: 9781139860567

Book DOI: https://doi.org/10.1017/CBO9781139860567
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Major depressive disorder (MDD) is the leading cause of disability globally in both developed and developing nations. The staggering economic costs attributable to MDD are largely a consequence of impairment in role function. Evidence indicates that disturbance in the domain of cognitive function in individuals with MDD is the principal determinant of health outcome. This is the first book to comprehensively explore the domain of cognition in MDD. The literature describing cognitive dysfunction is reviewed with particular focus on clinical determinants, pathophysiology and causative factors. The patient subpopulations most susceptible are defined. A summary of contemporary assessment tools for research and clinical purposes is provided. Multimodality treatments and prevention strategies are described. This book is an invaluable resource for psychiatrists, neuropsychologists and other members of the mental health team, as well as for policy makers, vocation rehabilitation experts, disability providers and other stakeholders interested in improving health outcomes in MDD.

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Cognitive Impairment in Major Depressive Disorder

Clinical Relevance, Biological Substrates, and Treatment Opportunities

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