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Chapter 2 - Pharmacology and Physiology in the Term Neonate

Published online by Cambridge University Press:  30 November 2019

By
Adam C. Adler  and
Ronald S. Litman
Edited by
Adam C. Adler ,
Arvind Chandrakantan  and
Ronald S. Litman
Adam C. Adler
Affiliation:
Texas Children's Hospital
Arvind Chandrakantan
Affiliation:
Texas Children's Hospital
Ronald S. Litman
Affiliation:
The Children's Hospital of Philadelphia
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Summary

This chapter, provides an overview of the basics of pharmacology and physiology in the neonate. The authors focus on the physiological differences between children and adults using a background case of omphalocele. Key concepts for pediatric anesthesia are considered including, hyperbilirubinemia, oxygenation, hepatic function and metabolism and thyroid function.

Keywords

gastroschisisomphaloceleneonatal hypoglycemiaBeckwith–Wiedemann syndromebilirubinjaundicecongenital hypothyroidismneonatal apneaneonatal liverneonatal coagulationneonatal opioid metabolismneonatal spinal.
Type
Chapter
Information
Case Studies in Pediatric Anesthesia , pp. 6 - 15
Publisher: Cambridge University Press
Print publication year: 2019

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References

Suggested Reading

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