Skip to main content Accessibility help
×
Hostname: page-component-848d4c4894-v5vhk Total loading time: 0 Render date: 2024-07-05T16:43:42.373Z Has data issue: false hasContentIssue false

2 - Motor and gestural disorders: Abnormal movement and motor behavior

Published online by Cambridge University Press:  10 October 2009

Luc Defebvre
Affiliation:
Hôpital Salengro, CHRU, France and University Hospital, Lille, France
Pierre Krystkowiak
Affiliation:
Hôpital Salengro, CHRU, France and University Hospital, Lille, France
Olivier Godefroy
Affiliation:
Université de Picardie Jules Verne, Amiens
Julien Bogousslavsky
Affiliation:
Université de Lausanne, Switzerland
Get access

Summary

Introduction

Focal brain lesions can induce several types of abnormal involuntary movement (AIM): dystonia, chorea, hemiballism, tremor, myoclonus, parkinsonism, and asterixis for example (Bhatia and Marsden, 1994; Lee and Marsden, 1994). The most frequent cause is stroke, followed by tumor, trauma, anoxia, vascular malformation, or multiple sclerosis. For some causes (and for stroke in particular), AIM can occur immediately after the brain lesion (for example, hemiballism during the acute phase of the stroke (Destée et al., 1990) whereas initial motor deficit may improve or be recovered rapidly. However, in other situations, AIMs (e.g. dystonia) emerge following a long period (a few months or years) of stable motor impairment (Marsden et al., 1985; Scott and Jankovic, 1996). AIMs can also be subdivided into transient (hemiballism, often in the acute phase) and persistent (dystonia, tremor, etc.). Whatever their timescales of appearance or disappearance, AIM may be the main symptom of stroke. This induces a delay in diagnosis or even a lack of knowledge of the specific diagnosis, since for the same underlying cause, the type of AIM can be quite different. This problem is sometimes clinically evident when the AIM is intense (hemiballism) or, in contrast, very moderate and focalized (asterixis). It is clear that a delay in diagnosis may have unhelpful consequences in terms of the patient's clinical and therapeutic management.

Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Andrew, J., Fowler, C. J. and Harrison, M. J. (1982). Tremor after head injury and its treatment by stereotaxic surgery. J. Neur. Neurosurg. Psychiatry, 45, 815–19.CrossRefGoogle ScholarPubMed
Bastian, A. J. and Thach, W. T. (1995). Cerebellar outflow lesions: a comparison of movement deficits resulting from lesions at the levels of the cerebellum and thalamus. Ann. Neurol., 38, 881–92.CrossRefGoogle ScholarPubMed
Benabid, A. L., Pollak, B., Gervason, C., et al. (1991). Long-term suppression of tremor by chronic stimulation of the ventral intermediate thalamic nucleus. Lancet, 337, 403–6.CrossRefGoogle ScholarPubMed
Bhatia, K. P., Lera, G., Luthert, P. J. and Marsden, C. D. (1994). Vascular chorea: case report with pathology. Mov. Disorders, 9, 447–50.CrossRefGoogle ScholarPubMed
Bhatia, K. P. and Marsden, C. D. (1994). The behavioral and motor consequences of focal lesions of the basal ganglia in man. Brain, 117, 859–76.CrossRefGoogle Scholar
Ceballos-Baumann, A. O., Passingham, R. E., Marsden, C. D. and Brooks, D. J. (1995). Motor reorganization in acquired hemidystonia. Ann. Neurol., 37, 746–57.CrossRefGoogle ScholarPubMed
Chung, S. J., Im, J. H., Lee, M. C. and Kim, J. S. (2004). Hemichorea after stroke: clinical-radiological correlation. J. Neurol., 251, 725–29.CrossRefGoogle ScholarPubMed
Cordivari, C., Misra, V. P., Catania, S. and Lee, A. J. (2004). New therapeutic indications for botulinum toxins. Mov. Disorders, 19(Suppl. 8), S157–S161.CrossRefGoogle ScholarPubMed
Defebvre, L., Destée, A., Cassim, F., Muller, J. P. and Vermersch, E. (1990). Transient hemiballism and striatal infarct. Stroke, 21, 967–8.Google ScholarPubMed
Demirkiran, M., Bozdemir, H. and Sarica, Y. (2001). Vascular parkinsonism: a distinct, heterogeneous clinical entity. Acta. Neurol. Scand., 104, 63–7.CrossRefGoogle ScholarPubMed
Destée, A., Muller, J. P., Vermersch, P., Pruvo, J. P. and Warot, P. (1990). Hémiballisme. Hémichorée. Infarctus striatal. Rev. Neurol., 146, 150–2.Google Scholar
Dewey, R. B. and Jankovic, J. (1989). Hemiballism-Hemichorea: Clinical and pharmacologic findings in 21. Arch. Neurol., 46, 862–7.CrossRefGoogle ScholarPubMed
Dooling, E. C. and Adams, R. D. (1975). The pathological anatomy of posthemiplegic athetosis. Brain, 98, 29–48.CrossRefGoogle ScholarPubMed
Fénélon, G. and Houéto, J. L. (1997). Unilateral parkinsonism following a large infarct in the territory of the lenticulostriate arteries. Mov. Disorders, 12, 1086–90.CrossRefGoogle ScholarPubMed
Fénélon, G. and Houéto, J. L. (1998). Les syndromes parkinsoniens vasculaires: un concept controversé. Rev. Neurol., 154, 291–302.Google Scholar
Flaherty, A. W. and Graybiel, A. M. (1994). Anatomy of the basal ganglia. In Movement Disorders 3, ed. Marsden, C. D. and Fahn, S.. Butterworth Heinemann Ltd., pp. 3–27.Google Scholar
Garcin, R. (1955). Syndrome cérébello-thalamique par lésion localisée du thalamus avec une digression sur le “signe de la main creuse” et son intérêt séméiologique. Rev. Neurol., 93, 143–9.Google Scholar
Ghika, J., Bogousslavski, J., Henerson, J., Maeder, P. and Regli, F. (1994). The “jerky dystonic unsteady hand”: a delayed motor syndrome in posterior thalamic infarctions. J. Neurol., 241, 537–42.CrossRefGoogle ScholarPubMed
Ghika-Smith, F., Ghika, J., Regli, F. and Bogousslavsky, J. (1997). Hyperkinetic movement disorders during and after acute stroke: the Lausanne Stroke Registry. J. Neurol. Sci., 146, 109–16.CrossRefGoogle Scholar
Growdon, H., Chambers, W. W. and Liu, C. N. (1967). An experimental dyskinesia in the rhesus monkey. Brain, 90, 603–32.CrossRefGoogle ScholarPubMed
Hopfensperger, K. J., Busenbark, K. and Koller, W. C. (1995). Midbrain tremor. In Handbook of Tremor Disorders, ed. Findley, L. J. and Koller, W. C.. New York, pp. 1455–9.Google Scholar
Hughes, A. J., Daniel, S. E. and Lees, A. J. (2001). Improved accuracy of clinical diagnosis of Lewy body parkinson's disease. Neurology, 57, 1497–9.CrossRefGoogle ScholarPubMed
Hunter, R., Smith, J., Thomson, T. and Dayan, A. D. (1978). Hemiparkinsonism with infarction of the ipsilateral substantia nigra. Neuropathol. Appl. Neurobiol., 4, 297–301.CrossRefGoogle ScholarPubMed
Johnson, W. G. and Fahn, S. (1977). Treatment of vascular hemiballism and hemichorea. Neurology, 27, 634–6.CrossRefGoogle ScholarPubMed
Kim, J. S. (1992). Delayed onset hand tremor caused by cerebral infarction. Stroke, 23, 292–4.CrossRefGoogle ScholarPubMed
Kim, J. S. (2001a). Asterixis after unilateral stroke: lesion location of 30 patients. Neurology, 56, 533–6.CrossRefGoogle Scholar
Kim, J. S. (2001b). Involuntary movements after anterior cerebral artery territory infarction. Stroke, 32, 258–61.CrossRefGoogle Scholar
Krystkowiak, P., Defebvre, L. and Destée, A. (1996). Vascular chorea causing a phenocopy of Huntington's disesase. 4th International Congress of Movement Disorders, June 17–21, 1996, Vienne. Movement Disorders, 11, 56.
Krystkowiak, P., Martinat, P., Cassim, F., et al. (2000). Thalamic tremor: correlations with 3D MRI data and pathophysiological mechanisms. Mov. Disorders, 15, 911–18.3.0.CO;2-B>CrossRefGoogle Scholar
Krystkowiak, P., Martinat, P., Defebvre, L., et al. (1998). Dystonia following thalamic and striatopallidal stroke: radioclinic correlations and pathophysiological mechanisms. J. Neurol. Neurosurg. Psychiatry, 65, 703–8.CrossRefGoogle Scholar
Leduc, V., Montagne, B. and Destée, A. (1997). Parkinsonism consecutive to an hemorrhagic lesion of the substantia nigra. Mov. Disorders, 12(Suppl. 1), 2.Google Scholar
Lee, M. S. and Marsden, C. D. (1994). Movement disorders following lesions of the thalamus or subthalamic region. Mov. Disorders, 9, 493–507.CrossRefGoogle ScholarPubMed
Leenders, K. L., Frackowiak, R. S., Quinn, N., et al. (1986). Ipsilateral blepharospasm and contralateral hemidystonia and parkinsonism in a patient with unilateral rostral brainstem-thalamic lesion: structural and functional abnormalities studied with CT, MRI and PET scanning. Mov. Disorders, 1, 51–8.CrossRefGoogle Scholar
Lehéricy, S., Grand, S., Pollak, P., et al. (2001). Clinical characteristics and topography of lesions in movement disorders due to thalamic lesions. Neurology, 57, 1055–66.CrossRefGoogle ScholarPubMed
Lehéricy, S., Vidailhet, M., Dormont, D., et al. (1996). Striatopallidal and thalamic dystonia: a magnetic resonance imaging anatomoclinical study. Arch. Neurol., 53, 241–50.CrossRefGoogle ScholarPubMed
Llinàs, R. and Paré, D. (1995). Role of intrinsic neuronal oscillations and network ensembles in the genesis of normal and pathological tremors. In Handbook of Tremor Disorders, ed. Findley, L. J. and Koller, W. C.. New York, pp. 7–36.Google Scholar
Marsden, C. D.Obeso, J. A.Zarranz, J. J. and Lang, A. E. (1985). The anatomical basis of symptomatic hemidystonia. Brain, 108, 463–83.CrossRefGoogle ScholarPubMed
Milhorat, T. H. (1967). Experimental myoclonus of thalamic origin. Arch. Neurol., 17, 365–78.CrossRefGoogle ScholarPubMed
Mitchell, I. J., Luquin, R., Boyce, S., et al. (1990). Neural mechanisms of dystonia: evidence from a 2-deoxyglucose uptake study in a primate model of dopamine agonist-induced dystonia. Mov. Disorders, 5, 49–54.CrossRefGoogle Scholar
Miwa, H., Hatori, K., Kondo, T., Imai, H. and Mizuno, Y. (1996). Thalamic tremor: case reports and implications of the tremor-generating mechanism. Neurology, 46, 75–9.CrossRefGoogle ScholarPubMed
Mizushima, N., Park-Matsumoto, Y. C., Amakawa, T. and Hayashi, H. (1997). A case of Hemichorea-Hemiballism associated with parietal lobe infarction. Eur. Neurol., 37, 65–6.CrossRefGoogle ScholarPubMed
Narbona, J.Obeso, J., Tunon, T., Martinez-Lage, J. M. and Marsden, C. D. (1984). Hemi-dystonia secondary to localised basal ganglia tumour. J. Neurol. Neurosurg. Psychiatry, 47, 704–9.CrossRefGoogle ScholarPubMed
Nijssen, P. C. and Tijssen, C. C. (1992). Stimulus-sensitive paroxysmal dyskinesias associated with a thalamic infarct. Mov. Disorders, 7, 364–6.CrossRefGoogle ScholarPubMed
Ohye, C., Shibazaki, T., Hirai, T., et al. (1989). Further physiological observations on the ventralis intermedius neurons in the human thalamus. J. Neurophysiol., 61, 488–500.CrossRefGoogle ScholarPubMed
Ondo, W. G., Chan, L. L. and Levy, J. K. (2002). Vascular parkinsonism: clinical correlates predicting motor improvement after lumbar puncture. Mov. Disorders, 17, 91–7.CrossRefGoogle ScholarPubMed
Oppenheimer, D. R. (1967). A case of striatal hemiplegia. J. Neurol. Neurosurg. Psychiatry, 30, 134–9.CrossRefGoogle ScholarPubMed
Percheron, G., Yelnik, J., Francois, C., Fenelon, G. and Talbi, B. (1994). Analyse informationnelle du système lié aux ganglions de la base. Rev. Neurol., 150, 614–26.Google Scholar
Peterson, D. I. and Peterson, G. W. (1987). Unilateral asterixis due to ispilateral lesions in the pons and medulla. Ann. Neurol., 22, 661–3.CrossRefGoogle Scholar
Pettigrew, L. C. and Jankovic, J. (1985). Hemidystonia: a report of 22 patients and a review of the literature. J. Neurol. Neurosurg. Psychiatry, 48, 650–7.CrossRefGoogle Scholar
Pullicino, P., Xuereb, M. and Farrugia, B. (1990). Hémorragie cérébelleuse et asterixis unilateral. Rev. Neurol., 146, 687–98.Google Scholar
Qureshi, F., Morales, A. and Elble, R. J. (1996). Tremor due to infarction in the ventrolateral thalamus. Mov. Disorders, 11, 440–59.CrossRefGoogle ScholarPubMed
Remy, P., Recondo, A., Defer, G., et al. (1995). Peduncular « rubral » tremor and dopaminergic denervation: a PET study. Neurology, 45, 472–7.CrossRefGoogle ScholarPubMed
Riley, D. E. (1996). Paroxysmal kinesigenic associated with a medullary lesion. Mov. Disorders, 11, 738–40.CrossRefGoogle ScholarPubMed
Scott, B. L. and Jankovic, J. (1996). Delayed-onset progressive movement disorders after static brain lesions. Neurology, 46, 68–74.CrossRefGoogle ScholarPubMed
Sethi, K. D., Nichols, F.T. and Yaghmai, F. (1987). Generalized chorea due to basal ganglia lacunar infarcts. Mov. Disorders, 2, 61–6.CrossRefGoogle ScholarPubMed
Sibon, I., Fénelon, G., Quinn, N. P. and Tison, F. (2004). Vascular parkinsonism. J. Neurol., 251, 513–24.CrossRefGoogle ScholarPubMed
Steriade, M., Currò-Dossi, R. and Nunez, A. (1991). Network modulation of a slow intrinsic oscillation of cat thalamocortical neurons implicated in sleep delta waves: cortically induced synchronization and brainstem cholinergic suppression. J. Neurosci., 11, 3200–17.CrossRefGoogle ScholarPubMed
Tabaton, M., Mancardi, G. and Loeb, C. (1985). Generalized chorea due to bilateral small, deep cerebral infarcts. Neurology, 35, 588–9.CrossRefGoogle ScholarPubMed
Tatu, L., Moulin, T., Martin, V., et al. (1996). Asterixis unilatéral et lésions cérébrales focales: douze cas. Rev. Neurol., 152, 121–7.Google Scholar
Trillet, M., Vighetto, A., Croisile, B., Charles, N. and Aimard, G. (1995). Hémiballisme avec libération thymo-affective et logorrhée par hématome du noyau sous-thalamique gauche. Rev. Neurol., 151, 416–19.Google Scholar
Trouillas, P. (1984). Regression of cerebellar syndrome with long term administration of 5-HTP or the combination 5-HTP-benzeraside. Ital. J. Neurol. Sci., 5, 253–66.CrossRefGoogle ScholarPubMed
Vidakovic, A., Dragasevic, N. and Kostic, V. S. (1994). Hemiballism: report of 25 cases. J. Neurol. Neurosurg. Psychiatry, 57, 945–9.CrossRefGoogle ScholarPubMed
Vidhailhet, M., Dupel, C., Lehericy, S., et al. (1999). Dopaminergic dysfunction in midbrain dystonia: anatomoclinical study using 3-dimensional magnetic resonance imaging and fluorodopa F 18 positron emission tomography. Arch. Neurol., 56, 982–9.CrossRefGoogle Scholar
Winikates, J. and Jankovic, J. (1999). Clinical correlates of vascular parkinsonism. Arch. Neurol., 56, 98–102.CrossRefGoogle ScholarPubMed
Yamanouchi, H. and Nagura, H. (1995). Cerebrovascular parkinsonism-clinicopathologic study. Rinsho Shinkeigaku, 35, 1457–8.Google ScholarPubMed
Yoshimura, D. M., Aminoff, M. J. and Olney, R. K. (1992). Botulinum toxin therapy for limb dystonias. Neurology, 42, 627–30.CrossRefGoogle ScholarPubMed
Zagnoli, F., Rouhart, F., Perotte, P., Bellard, S. and Goas, J. Y. (1996). Hémichorée et infarctus striatal. Rev. Neurol., 152, 615–22.Google Scholar
Zijlmans, J. M. C., Thijssen, H. O. M., Vogels, O. J. M., et al. (1995). MRI in patients with suspected vascular parkinsonism. Neurology, 45, 2183–8.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×