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Bone infarcts (medullary)

from Section I - Musculoskeletal radiology

Published online by Cambridge University Press:  22 August 2009

James R. D. Murray
Affiliation:
Bath Royal United Hospital
Erskine J. Holmes
Affiliation:
Royal Berkshire Hospital
Rakesh R. Misra
Affiliation:
Buckinghamshire Hospitals NHS Trust
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Summary

Characteristics

  • Idiopathic bone infarcts characteristically occur in long-bone metaphyses.

  • Histological testing reveals mineralisation of necrotic marrow.

  • Aetiology is likely to be related to intrinsic/extrinsic vascular compromise such as thrombosis, arteritis, atherosclerosis or external compression (fractures, oedema, tumour, etc).

Clinical features

  • Classically asymptomatic and discovered as an incidental diagnosis.

Radiological features

  • Early rarefaction followed by sclerosis, calcification, and ossification parallel to the cortex in the healing phase.

  • Bone scan – ‘cold spot’ or no increased uptake in the early stages; becomes ‘hot’ as revascularisation occurs.

Management

  • No treatment is required; however, malignant fibrous histiocytoma has been reported developing in previous bone infarcts.

Bone islands

Characteristics

  • Histologically these are markedly thickened bony trabeculae.

  • Seen in all ages.

  • Unknown aetiology but may represent a developmental anomaly.

  • Usually solitary, commonest in the proximal femur and ilium.

Clinical features

  • Asymptomatic – incidental diagnosis, but these are important in the differential diagnosis of more sinister lesions.

Radiological features

  • Sclerotic areas within bone which are well demarcated from surrounding normal bone (narrow zone transition). Classically the margin appears feathery.

  • No cortical involvement or periosteal reaction.

  • Often oval with the long axis parallel to the bone.

  • Bone scan – if large may show increased uptake.

Management

  • Exclude more sinister pathology, but no particular treatment is required.

Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2008

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