Skip to main content Accessibility help
×
Hostname: page-component-7c8c6479df-995ml Total loading time: 0 Render date: 2024-03-29T01:21:47.441Z Has data issue: false hasContentIssue false

Chapter 6 - Pharmacogenetics in psychiatry

Published online by Cambridge University Press:  05 October 2012

John I. Nurnberger, Jr
Affiliation:
Indiana University School of Medicine
Wade Berrettini
Affiliation:
University of Pennsylvania School of Medicine
Get access

Summary

This chapter describes the recent developments in the field of psychiatric pharmacogenetics. Most pharmacogenetic studies of antidepressants have focused predominantly on treatment response, perhaps also due to the fact that most current antidepressants are well tolerated and fairly safe. Pharmacotherapy is the treatment of choice for psychotic symptoms of mental conditions such as schizophrenia, bipolar disorder, and psychotic depression. Antipsychotic drugs are traditionally divided into two groups: typical (first-generation) antipsychotics, with strong affinity for the dopamine receptor, and atypical (second-generation) antipsychotics, with multiple receptor targets. Anticonvulsant drugs are widely used in the management of behavioral disorders, including bipolar disorder, mood disorders, and impulse control disorders. While psychiatry has entered the new area of pharmacogenetics, it is important to remember that this new technology will only provide additional information on one aspect of the complex and personal history of psychiatric patients.
Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2012

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×