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Case 92 - Chondroblastoma

from Section 12 - Tumors/Miscellaneous

Published online by Cambridge University Press:  05 July 2013

D. Lee Bennett
Affiliation:
University of Iowa
Georges Y. El-Khoury
Affiliation:
University of Iowa
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Summary

Imaging description

In flat bones chondroblastoma is reported to occur in the acetabular region, scapula, ribs, patella, talus, and calcaneus (Figure 92.1).

The epiphyseal location for most chondroblastomas is an important diagnostic imaging feature; the lesion often traverses the epiphyseal plate into the metaphyseal region (Figure 92.2). Radiographically a chondroblastoma reveals a geographic lytic lesion measuring about 2–5 cm in diameter. The majority of chondroblastomas have a thin sclerotic border. Local thinning and expansion of the overlying cortical bone is a common finding. In a study by Brower et al. they observed a periosteal reaction distal to the tumor in 47% of chondroblastomas. The periosteal reaction is usually thick, solid, or layered, and its presence was helpful in distinguishing chondroblastoma from other epiphyseal lesions.

On MRI a chondroblastoma shows low to intermediate signal intensity lesion on T1-weighted images, whereas T2-weighted images show low, high, or heterogeneous signal intensity. Another imaging finding which is important in arriving at the correct diagnosis is the commonly associated bone marrow edema which presents with low signal intensity on T1-weighted images and increased signal intensity on T2-weighted images (Figure 92.3). After intravenous administration of gadolinium the edematous marrow shows enhancement on fat-suppressed T1-weighted images. Edema has also been described involving the soft tissues adjacent to the chondroblastoma. Another sign of inflammation, in addition to the edema in the bone marrow and soft tissues, is the presence of synovitis and joint effusion in the adjacent joint.

Type
Chapter
Information
Pearls and Pitfalls in Musculoskeletal Imaging
Variants and Other Difficult Diagnoses
, pp. 241 - 245
Publisher: Cambridge University Press
Print publication year: 2013

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References

Azorin, D, Gonzalez-Mediero, I, Colmenero, I et al. Diaphyseal chondroblastoma in a long bone: first report. Skeletal Radiol 2006;35:49–52.CrossRefGoogle Scholar
Bloem, JL, Mulder, JD.Chondroblastoma: a clinical and radiological study of 104 cases. Skeletal Radiol 1985;14:1–9.CrossRefGoogle ScholarPubMed
Brower, AC, Moser, RP, Kransdorf, MJ.The frequency and diagnostic significance of periostitis in chondroblastoma. AJR Am J Roentgenol 1990;154:309–314.CrossRefGoogle ScholarPubMed
Hayes, CW, Conway, WF, Sundaram, M.Misleading aggressive MR imaging appearance of some benign musculoskeletal lesions. RadioGraphics 1992;12:1119–1134.CrossRefGoogle ScholarPubMed
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Kim, J, Kumar, R, Raymond, AK, Ayala, AG.Non-epiphyseal chondroblastoma arising in the iliac bone, and complicated by an aneurysmal bone cyst: a case report and review of the literature. Skeletal Radiol 2010;39:583–587.CrossRefGoogle ScholarPubMed
Kyriakos, M, Land, VJ, Penning, HL, Parker, SG.Metastatic chondroblastoma report of a fatal case with a review of the literature on atypical, aggressive, and malignant chondroblastoma. Cancer 1985;55:1770–1789.3.0.CO;2-Q>CrossRefGoogle ScholarPubMed
Ramappa, AJ, Lee, FYI, Tang, P et al. Chondroblastoma of bone. J Bone Joint Surg 2000;82-A:1140–1145.CrossRefGoogle ScholarPubMed
Yamamura, S, Sato, K, Sugiura, H, Iwata, H.Inflammatory reactive in chondroblastoma. Skeletal Radiol 1996;25:371–376.CrossRefGoogle ScholarPubMed

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  • Chondroblastoma
  • Edited by D. Lee Bennett, University of Iowa, Georges Y. El-Khoury, University of Iowa
  • Book: Pearls and Pitfalls in Musculoskeletal Imaging
  • Online publication: 05 July 2013
  • Chapter DOI: https://doi.org/10.1017/CBO9781139031141.094
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  • Chondroblastoma
  • Edited by D. Lee Bennett, University of Iowa, Georges Y. El-Khoury, University of Iowa
  • Book: Pearls and Pitfalls in Musculoskeletal Imaging
  • Online publication: 05 July 2013
  • Chapter DOI: https://doi.org/10.1017/CBO9781139031141.094
Available formats
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  • Chondroblastoma
  • Edited by D. Lee Bennett, University of Iowa, Georges Y. El-Khoury, University of Iowa
  • Book: Pearls and Pitfalls in Musculoskeletal Imaging
  • Online publication: 05 July 2013
  • Chapter DOI: https://doi.org/10.1017/CBO9781139031141.094
Available formats
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