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Chapter 1 - Individualized Ovarian Stimulation for Normal and High Responders

Published online by Cambridge University Press:  12 February 2021

By
Laura Melado  and
Human M. Fatemi
Edited by
Human M. Fatemi  and
Barbara Lawrenz
Human M. Fatemi
Affiliation:
IVI Middle East Fertility Clinic, Abu Dhabi, UAE
Barbara Lawrenz
Affiliation:
IVI Middle East Fertility Clinic, Abu Dhabi, UAE
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Summary

Despite the notion that the first baby, Louise Brown, was born in 1978 following IVF performed in a natural menstrual cycle, ovarian stimulation became the golden standard of care in clinical IVF, since the number of oocytes retrieved is directly associated with pregnancy and life birth rates (, ). The aim should be to titrate the stimulation in such a way that the optimal number of follicles develops. Too few follicles (also referred to as low response) usually means poor IVF outcome, whereas too many developing follicles induce a risk for developing OHSS and possibly reduce the chance of success with increasing number of oocytes, if stimulation is not adjusted toward the end of the follicular phase (, ).

Type
Chapter
Information
Individualized In-Vitro Fertilization
Delivering Precision Fertility Treatment
 , pp. 1 - 13
Publisher: Cambridge University Press
Print publication year: 2021

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References

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