Skip to main content Accessibility help
×
Hostname: page-component-5c6d5d7d68-pkt8n Total loading time: 0 Render date: 2024-08-17T03:23:20.913Z Has data issue: false hasContentIssue false

Chapter 22 - Immune Paralysis and Reconstitution after Hematopoietic Cell Transplants

from Section 7 - Other Complications of Hematopoietic Cell Transplants

Published online by Cambridge University Press:  24 May 2017

Hillard M. Lazarus
Affiliation:
Case Western Reserve University, Ohio
Robert Peter Gale
Affiliation:
Imperial College London
Armand Keating
Affiliation:
University of Toronto
Andrea Bacigalupo
Affiliation:
Ospedale San Martino, Genoa
Reinhold Munker
Affiliation:
Louisiana State University, Shreveport
Kerry Atkinson
Affiliation:
University of Queensland
Syed Ali Abutalib
Affiliation:
Midwestern Regional Medical Center, Cancer Treatment Centers of America, Chicago
Get access
Type
Chapter
Information
Hematopoietic Cell Transplants
Concepts, Controversies and Future Directions
, pp. 195 - 200
Publisher: Cambridge University Press
Print publication year: 2000

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bosch, M., and Storek, J.. Immune reconstitution after hematopoietic cell transplantation. Curr Opin Hematol 2012; 19:324–35.CrossRefGoogle ScholarPubMed
Savani, B. N., Adams, S., Uribe, M., et al. Rapid natural killer cell recovery determines outcome after T-cell-depleted HLA-identical stem cell transplantation in patients with myeloid leukemias but not with acute lymphoblastic leukemia. Leukemia 2007; 21:2145–52.CrossRefGoogle Scholar
Le Blanc, K., Schaffer, M., Hägglund, H., et al. Lymphocyte recovery is a major determinant of outcome after matched unrelated myeloablative transplantation for myelogenous malignancies. Biol Blood Marrow Transplant 2009; 15:1108–15.Google Scholar
Michelis, F. V., Loach, D., Uhm, J., et al. Early lymphocyte recovery at 28 d post-transplant is predictive of reduced risk of relapse in patients with acute myeloid leukemia transplanted with peripheral blood stem cell grafts. Eur J Haematol 2014; 93(4):273–80. .CrossRefGoogle ScholarPubMed
Burke, M. J., Janardan, S. K., Brunstein, C., et al. Early lymphocyte recovery and outcomes after umbilical cord blood transplantation (UCBT) for hematologic malignancies. Biol Blood Marrow Transplant 2011; 17:831–40.CrossRefGoogle ScholarPubMed
Komanduri, K. V., de Lima, M., McMannis, J., et al. Delayed immune reconstitution after cord blood transplantation is characterized by impaired thymopoiesis and late memory T-cell skewing. Blood 2007; 110:4543–51.CrossRefGoogle ScholarPubMed
Satpathy, A. T., Albring, J. C., and Murphy, K. M.. Re(de)fining the dendritic cell lineage. Nat Immunol 2012; 13:1145–54.CrossRefGoogle ScholarPubMed
Ruggeri, L., Urbani, E., Perruccio, K., et al. Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science 2002; 295:2097–100.CrossRefGoogle ScholarPubMed
Ruggeri, L., Burchielli, E., Capanni M, M., et al. NK cell alloreactivity and allogeneic hematopoietic stem cell transplantation. Blood Cells Mol Dis 2008; 40:8490.CrossRefGoogle ScholarPubMed
Chang, Y. J., and Huang, X. J.. Effects of the NK cell recovery on outcomes of unmanipulated haploidentical blood and marrow transplantation for patients with hematologic malignancies. Biol Blood Marrow Transplant 2008; 14:323–34.CrossRefGoogle ScholarPubMed
Della Chiesa, M., Muccio, L., Bertaina, A., et al. Impact of HCMV infection on NK cell development and function after HCT. Front Immunol 2013; 4:458.CrossRefGoogle Scholar
Gudiol, C., Arnan, M., Sánchez-Ortega, I., et al. Etiology, clinical features and outcomes of pre-engraftment and post-engraftment bloodstream infection in hematopoietic SCT recipients. Bone Marrow Transplant 2014; 49:824−30.CrossRefGoogle ScholarPubMed
Mackall, C., Gress, R., Peggs, K., et al; Center for International Blood and Marrow Transplant Research (CIBMTR); National Marrow Donor Program (NMDP); European Blood and Marrow Transplant Group (EBMT); American Society of Blood and Marrow Transplantation (ASBMT); Canadian Blood and Marrow Transplant Group (CBMTG); Infectious Disease Society of America (IDSA); Society for Healthcare Epidemiology of America (SHEA); Association of Medical Microbiology and Infectious Diseases Canada (AMMI); Centers for Disease Control and Prevention (CDC). Background to hematopoietic cell transplantation, including post transplant immune recovery. Bone Marrow Transplant 2009; 44:457–62.CrossRefGoogle ScholarPubMed
Fozza, C.. T-cell receptor repertoire usage in hematologic malignancies. Crit Rev Oncol Hematol 2013; 86:201–11.CrossRefGoogle ScholarPubMed
Kim, D. H., Won, D. I., Lee, N. Y., et al. Rapid helper T-cell recovery above 200 x 10 6/l at 3 months correlates to successful transplant outcomes after allogeneic stem cell transplantation. Bone Marrow Transplant 2006; 37:1119–28.CrossRefGoogle ScholarPubMed
Fedele, R., Garreffa, C., Messina, G., et al. The impact of early CD4+ lymphocyte recovery on the outcome of patients who undergo allogeneic bone marrow or peripheral blood stem cell transplantation. Blood Transfus 2012; 10:174–80.Google ScholarPubMed
Six A, A., Chaara, W., Magadan, S., et al. The past, present, and future of immune repertoire biology − the rise of next-generation repertoire analysis. Front Immunol 2013; 4:413.Google ScholarPubMed
Krenger, W., and Holländer, G. A.. Thymic T-cell development in allogeneic stem cell transplantation. Blood 2011; 117:6758–76.CrossRefGoogle ScholarPubMed
Ringhoffer, S., Döhner, H., Bunjes, D., et al. T-cell reconstitution after allogeneic stem cell transplantation: assessment by measurement of the sjTREC/βTREC ratio and thymic naive T cells. Haematologica 2013; 98:1600–8.CrossRefGoogle ScholarPubMed
Toubert, A., Douay, C., and Clave, E.. Thymus and immune reconstitution after allogeneic hematopoietic stem cell transplantation in humans: never say never again. Tissue Antigens 2012; 79:83–9.CrossRefGoogle Scholar
Rueff, J., Heim, D., Passweg, J., et al. Lymphocyte subset recovery and outcome after autologous hematopoietic stem cell transplantation for plasma cell myeloma. Biol Blood Marrow Transplant 2014; 20:869–9.CrossRefGoogle ScholarPubMed
Muraro, P., Malhotra, S., Howell, M., et al. T cell repertoire following autologous stem cell transplantation for multiple sclerosis. J Clin Invest 2014; 124:1168–72.CrossRefGoogle ScholarPubMed
Ciurea, S. O., Saliba, R. M., Bayraktar, U. D., et al. Improved early outcomes using a T cell replete graft compared with T cell depleted haploidentical hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2012; 18:1835–44.CrossRefGoogle Scholar
Chevallier, P., Illiaquer, M., Esbelin, J., et al. Characterization of various blood and graft sources: a prospective series. Transfusion 2013; 53:2020–6.CrossRefGoogle ScholarPubMed
Escalón, M. P.. Cord blood transplantation: evolving strategies to improve engraftment and immune reconstitution. Curr Opin Oncol 2010; 22:122–9.CrossRefGoogle ScholarPubMed
Gärtner, F., Finke, J., and Bertz, H.. Lowering the alemtuzumab dose in reduced intensity conditioning allogeneic hematopoietic cell transplantation is associated with a favorable early intense natural killer cell recovery. Cytotherapy 2013; 15:1237–44.CrossRefGoogle ScholarPubMed
Streitz, M., Kapinsky, M., Reed, M., et al. Standardization of whole blood immune phenotype monitoring for clinical trials: panels and methods from the ONE study. Transplant Res 2013; 2:17.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×