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Chapter 27 - Toxicology of the Elder

Published online by Cambridge University Press:  11 July 2020

Kim A. Collins
Affiliation:
LifePoint Inc, South Carolina
Roger W. Byard
Affiliation:
University of Adelaide
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Summary

The older adult population is growing in all regions of the world. According to the World Health Organization (WHO), by the year 2050 there will be a global population of 2 billion that are 60 years of age and older [1]. In part, earlier detection of clinical disease, better access to treatment options, and advances in pharmaceutical development have fostered this evolution.

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Publisher: Cambridge University Press
Print publication year: 2020

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References

World Health Organization (2018) Ageing and Health. www.who.int/news-room/fact-sheets/detail/ageing-and-health (accessed June 28, 2018).Google Scholar
Hunt, R.H., Camilleri, M., Crowe, S.E., et al. (2015) The stomach in health and disease. Gut, 64, 16501668.Google Scholar
Krasinski, S.D., Russell, R.M., Samloff, I.M., et al. (1986) Fundic atrophic gastritis in an elderly population. Effect on hemoglobin and several serum nutritional indicators. Journal of the American Geriatrics Society, 34, 800806.CrossRefGoogle Scholar
Winek, C.L. and Carfagna, M. (1987) Comparison of plasma, serum, and whole blood ethanol concentrations. Journal of Analytical Toxicology, 11, 267268.Google Scholar
Cockcroft, D.W. and Gault, M.H. (1976) Prediction of creatinine clearance from serum creatinine. Nephron, 16, 3141.Google Scholar
Masnoon, N., Shakib, S., Kalisch-Ellett, L. and Caughey, G.E. (2017) What is polypharmacy? A systematic review of definitions. BMC Geriatrics, 17, 230.Google Scholar
By the American Geriatrics Society 2015 Beers Criteria Update Expert Panel (2015) American Geriatrics Society 2015 Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults. Journal of the American Geriatrics Society, 63, 22272246.CrossRefGoogle Scholar
Geriatrics Care (2018) Geriatric Resources. Online events. Updates – Geriatrics Care Online. https://geriatricscareonline.org/FullText/B023/B023_VOL001_PART001_SEC004_CH032 (accessed June 28, 2018).Google Scholar
Yap, A.F., Thirumoorthy, T. and Kwan, Y.H. (2016) Medication adherence in the elderly. Journal of Clinical Gerontology and Geriatrics, 7, 6467.Google Scholar
Nguyen, P.V.-Q. and Spinelli, C. (2016) Prescribing cascade in an elderly woman. Canadian Pharmacists Journal, 149, 122124.Google Scholar
Rochon, P.A. and Gurwitz, J.H. (1997) Optimising drug treatment for elderly people: the prescribing cascade. BMJ, 315, 10961099.CrossRefGoogle ScholarPubMed
Locquet, M., Honvo, G., Rabenda, V., et al. (2017) Adverse health events related to self-medication practices among elderly: a systematic review. Drugs & Aging, 34, 359365.Google Scholar
WebMD. Drug Interaction Checker – Find Interactions Between Medications. www.webmd.com/interaction-checker/default.htm (accessed 28, June 2018).Google Scholar
Drugs.com. Drug Interactions Checker – For Drugs, Food & Alcohol. www.drugs.com/drug_interactions.html (June 28, 2018).Google Scholar
American Psychological Association. Elder Abuse. www.apa.org/pi/prevent-violence/resources/elder-abuse.aspx (June 28, 2018).Google Scholar
Simone, L., Wettstein, A., Senn, O., Rosemann, T. and Hasler, S. (2016) Types of abuse and risk factors associated with elder abuse. Swiss Medical Weekly, 146, w14273.Google Scholar
Klausz, G., Kass, K., Sótonyi, P. and Róna, K. (2006) [Hair analysis of abused and therapeutic drugs in forensic toxicology]. Orvosi Hetilap, 147, 21812186.Google Scholar
Byard, R.W. and Musgrave, I. Herbal medicines and forensic investigations. Forensic Science, Medicine and Pathology, 2010; 6: 8182.CrossRefGoogle ScholarPubMed
Nikolaou, P., Papoutsis, I., Dona, A., Spiliopoulou, C. and Athanaselis, S. (2013) Toxicological analysis of formalin-fixed or embalmed tissues: a review. Forensic Science International, 233, 312319.Google Scholar
Krashin, D., Murinova, N., Jumelle, P. and Ballantyne, J. (2015) Opioid risk assessment in palliative medicine. Expert Opinion on Drug Safety, 14, 10231033.Google Scholar
Levine, B., King, T., Pestaner, J.P. and Smialek, J.E. (2001) Palliative pain therapy at the end of life and forensic medicine issues. The American Journal of Forensic Medicine and Pathology, 22, 6264.Google Scholar
Andresen, B.D., Alcaraz, A. and Grant, P.M. (2005) The application of pancuronium bromide (Pavulon) forensic analyses to tissue samples from an ‘Angel of Death’ investigation. Journal of Forensic Sciences, 50, 215219.Google Scholar
Cook, D.S., Braithwaite, R.A. and Hale, K.A. (2000) Estimating antemortem drug concentrations from postmortem blood samples: the influence of postmortem redistribution. Journal of Clinical Pathology, 53, 282285.CrossRefGoogle ScholarPubMed

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