Skip to main content Accessibility help
×
Home
Hostname: page-component-544b6db54f-vq995 Total loading time: 0.319 Render date: 2021-10-17T03:21:57.754Z Has data issue: true Feature Flags: { "shouldUseShareProductTool": true, "shouldUseHypothesis": true, "isUnsiloEnabled": true, "metricsAbstractViews": false, "figures": true, "newCiteModal": false, "newCitedByModal": true, "newEcommerce": true, "newUsageEvents": true }

4 - Touch and Hearing

Published online by Cambridge University Press:  23 February 2017

Lewis I. Held, Jr
Affiliation:
Texas Tech University
Get access

Summary

This chapter reveals parallels between the human ear and the fly ear (1) at the organ level in terms of tissue architecture, (2) at the tissue level in terms of development, (3) at the cellular level in terms of mechanosensory transduction, and (4) at the genetic level in terms of area-code specification and cell-type licensing. It also delves into the genetic pathways by which cells orient themselves within epithelia. Virtually all animals rely on the same two planar cell polarity (PCP) pathways to inform cells about the axes of the organs wherein they reside. The more familiar one is the core PCP circuit with 6 proteins, but there is another (non-core) circuit that uses 3 other proteins. One mystery that is explored here concerns an enigmatic line of symmetry in the utricle of the human inner ear. That line bisects the lawn of sensory hairs in the macula but its origin and function are unclear. To try to make sense of it, a similar line of symmetry in the fly eye is analyzed as a case study. Another (more opaque) mystery concerns how genomes establish area codes in epithelia in general. For that excursion a different case study is used (the fly's achaete-scute complex).
Type
Chapter
Information
Deep Homology?
Uncanny Similarities of Humans and Flies Uncovered by Evo-Devo
, pp. 85 - 102
Publisher: Cambridge University Press
Print publication year: 2017

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Send book to Kindle

To send this book to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.

Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

  • Touch and Hearing
  • Lewis I. Held, Jr, Texas Tech University
  • Book: Deep Homology?
  • Online publication: 23 February 2017
  • Chapter DOI: https://doi.org/10.1017/9781316550175.007
Available formats
×

Send book to Dropbox

To send content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about sending content to Dropbox.

  • Touch and Hearing
  • Lewis I. Held, Jr, Texas Tech University
  • Book: Deep Homology?
  • Online publication: 23 February 2017
  • Chapter DOI: https://doi.org/10.1017/9781316550175.007
Available formats
×

Send book to Google Drive

To send content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about sending content to Google Drive.

  • Touch and Hearing
  • Lewis I. Held, Jr, Texas Tech University
  • Book: Deep Homology?
  • Online publication: 23 February 2017
  • Chapter DOI: https://doi.org/10.1017/9781316550175.007
Available formats
×