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Chapter 54 - Local Anesthetic Systemic Toxicity (LAST)

Published online by Cambridge University Press:  30 November 2019

Adam C. Adler
Affiliation:
Texas Children's Hospital
Arvind Chandrakantan
Affiliation:
Texas Children's Hospital
Ronald S. Litman
Affiliation:
The Children's Hospital of Philadelphia
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Summary

This chapter reviews the thankfully rare but critical topic of local anesthetic systemic toxicity in children. The authors discuss the incidence, presentation and differential diagnosis related to local anesthetic toxicity. The chapter discusses the prevention and treatment of local anesthetic toxicity which is crucial knowledge for providers performing regional anesthesia in children.

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Chapter
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Publisher: Cambridge University Press
Print publication year: 2019

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References

Suggested Reading

Neal, JM, Bernards, CM, Butterworth, JF 4th, et al. ASRA practice advisory on local anesthetic systemic toxicity. Reg Anesth Pain Med. 2010;35(2):152–61. PMID: 20216033.CrossRefGoogle ScholarPubMed
Weinberg, GL. Lipid emulsion infusion: resuscitation for local anesthetic and other drug overdose. Anesthesiology. 2012;117:180–7. PMID: 22627464.CrossRefGoogle ScholarPubMed
Weinberg, GL. Treatment of local anesthetic systemic toxicity (LAST). Reg Anesth Pain Med. 2010;35:188–93. PMID: 20216036.CrossRefGoogle ScholarPubMed

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