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A 63-year-old woman was referred because of decreased strength of her right leg manifesting with buckling of the knee for the past five years. Sometimes this led to falls, which made her feel insecure while walking. She experienced some aching in her right heel and in her right knee after long walks. She was able to walk for two hours. She and her husband loved to walk in the mountains, and during those hikes she used a cane. The previous history is relevant because at age 5 years she had suffered from poliomyelitis anterior acuta, which had affected both legs. She had a partial recovery in the sense that she regained normal strength of her left leg and was left with residual weakness of her right leg. She underwent surgery at age 10 years (ankle arthrodesis on the right and epiphysiodesis of the left leg).
A 53-year-old man developed a left-sided foot drop and a painful sensation on the ventral side of the foot and outer part of the lower leg. Two weeks later, the same symptoms also developed on the right side. In addition, he noticed progressive numbness of his lower legs. Three weeks later, he noticed weakness of his right hand, and was unable to spread his fingers. He had no other symptoms, and his medical history was not informative. He did not recall a tick bite or erythema migrans, or any pulmonary abnormality, and had not visited tropical countries. He does not sit with crossed legs.
The Intergovernmental Panel on Climate Change (IPCC) is one of the most significant global assessment bodies established, and it provides the most authoritative and influential assessments of climate change knowledge. This book examines the history and politics of the organisation, and how this shapes its assessment practice and the climate knowledge it produces. Developing a new methodology, this book focuses on the actors, activities, and forms of authority affecting the IPCC's constructions of climate change. It describes how social, economic, and political dynamics influence all aspects of the organisation and its work. The book contributes to understanding the place of science in politics and politics in science, and offers important insights for designing new knowledge bodies for global environmental agreement-making. It is indispensable for students and researchers in environmental studies, international relations, and political science, as well as policymakers and anyone interested in the IPCC.
This chapter focuses on quantitative EEG processing, also known as EEG trend analysis. These types of algorithms process raw EEG data in a quantitative way, and display the data in more compressed forms that may be easier for the amateur EEG reader to interpret. Specific QEEG algorithms described in this chapter include amplitude integrated EEG, FFT spectrogram, rhythmicity spectrogram, asymmetry indices, and seizure detectors. Specific roles for QEEG covered include seizure detection and detection of focal cerebral ischemia.
The prism adaptation (PA) with rightward shifting lenses is a promising rehabilitation technique for left hemispatial neglect. The PA has also been applied in healthy individuals to investigate cognitive mechanism(s) underlining such adaptation. Importantly, studies have suggested that PA may primarily impact the functions of the dorsal or the ventral attentional stream, and we have previously reported that PA to the upward and downward shifting lenses leads to a significant aftereffect in vertical line bisection task. However, this post-adaptation effect, similarly to that seen in the horizontal plane, might have been modified by the presence of the vertical pseudoneglect healthy participants often experience prior to PA. Thus, the aim of this study was to test this hypothesis.
Participants and Methods:
30 right-handed healthy adults (age M=22,4) performed a computerized line bisection (LB) in vertical and horizontal condition. The bisections were performed twice: before and after PA procedure. Participants took experimental procedure three times, each in at least 24 h of break, each time in one of three conditions of shifting lenses; down, up, control. Both LB tasks (vertical and horizontal) consisted of 24 lines, each centered on 23" touch screen. The participants were asked to find the middle of the line. Throughout the experiment, participants were comfortably seated with their head positioned on a chinrest. Participants were fitted with prismatic goggles that deviated their visual field by 10 degrees. For the adaptation we used the Peg-the-mole procedure consisting of 120 pointing movements.
Results:
To assess the effect of the vertical PA on landmark judgments we performed a repeated measures ANOVA with direction of PA (upward/downward), the condition of LB (vertical/ horizontal) and pre- vs post adaptation as a between-subjects factor. This analysis revealed a main effect of the direction of PA (p< 0.001) and a main effect of condition (p< 0.001). Overall, however, only adaptation in up-shifting lenses led to significant aftereffects (p<0.05). Further, when we excluded participants who did not exhibited horizontal pseudoneglect in preadaptation LB, the effect of PA in downshifting PA emerged in vertical LB (p<0.05). Further, this group also exhibited the aftereffect of PA in up-shifting lenses for the horizontal (p<0.01) and the vertical LB (p<0.05). Additionally, these participants exhibited a congruent tendency after upward and downward PA, and tended to allocate their attention more upward and rightward.
Conclusions:
The results of this study confirm that the vertical PA evokes a visuo-spatial bias. Moreover, the PA aftereffect seems to be modified by the presence of the pre-adaptation pseudoneglect. Whereas the mechanism inducing this bias is not fully known, it might be explained in light of the interhemispheric activation-inhibition balance. Both the upward and downward PA may primarily lead to activation of the posterior regions of the right hemisphere, and this activation may result with the upward and rightward bias in the LB task. However, future research with neuroimaging techniques is needed to test this hypothesis.
Chapter 4 explores cross-linguistic variation in the language of space along with the potential implications of this variation for the spatial conceptualization of time.
In the wake of the intensifying Sino–Japanese rivalry in Asia, a new third-party market cooperation (TPMC) framework emerged in late 2018. The new mechanism was inaugurated around the time of former Japanese Prime Minister Shinzo Abe's visit to Beijing, displaying new attempts at Sino–Japanese economic diplomacy. Nonetheless, this article highlights the absence of major cooperative outcomes and suggests a pessimistic vision of TPMC's future, as three pairs of politico-economic gaps have led to asymmetries in the approaches adopted by China and Japan. First, a government-to-government policy asymmetry occurred between China's initiatives and Japan's responsiveness, as the latter merely utilized the TPMC as a temporary diplomatic tool to restore bilateral relations in late 2018 and appeared to have lost its policy momentum in the following years. Second, asymmetries in business modes and investment management between the two countries' enterprises have led to technical barriers in materializing the two governments' agreements into specific TPMC business collaboration. This study illustrated a project of Sino–Japanese collaboration in building a high-speed railway in Thailand, and saw this failed case as a warning for existing gaps of commercial modes. Third, both countries are now confronted with domestic underdeveloped public–private partnerships between state and private sectors. This article also aims to provide some policy-oriented implications for steadily implementing the Sino–Japanese TPMC in the future.
Given China’s position in Pacific Asia, defining its regional centrality might seem a simple task. But centralities grander than merely geographical have been alleged and contested. Currently some maintain that China is the central kingdom because of its power. But it was conquered by the Mongols and the Manchus, and its present centrality is due more to its economic mass and connectivity than to its military. Others claim that hierarchy is natural to Asian culture, and China is the apex. But neighbors were often cynical about China’s moral stature, and China’s soft power is now at a low ebb. I argue that China was the center of regional attention in the premodern era, and that it has returned to center stage since 2008. The three basic reasons for China’s original centrality and its return were situational: presence, population, and production. The salience of all three disappeared with Western imperialism’s global presence, the devaluation of mere demography, and industrial production. Traditional and current centrality created asymmetric relationships between China and its neighbors, but the regional situations differ fundamentally.
Pacific Asia, comprised of Northeast Asia, Greater China, and Southeast Asia, has surpassed the combined production of the United States and Europe, and its intraregional economic cohesiveness exceeds that of either the EU or North America. Pacific Asia has emerged gradually and without major conflict, but it should be taken seriously as a region. China is primarily a regional power, but in a prosperous region deeply interconnected to the rest of the world. The United States tends to view China as a lone global competitor, but its global presence and strength rest on its centrality to Pacific Asia. Understanding China in its region is the first task of this book, followed by the challenge of rethinking the global order in terms of a multinodal matrix rather than a bipolar competition of great powers. This requires background on the evolution of the Pacific Asian configuration, including China’s premodern centrality as well as the splintering of the region by European colonialism. Rethinking is aided by commentaries from four of Asia’s leading thinkers about international relationships.
While Pacific Asia had China as a “solid center,” a place in the middle where most of the people and production was, the West had a “liquid center,” the Mediterranean. Wealth could be pursued and neighbors conquered in different places in the West, leading to competitive, distinct empires rather than to dynastic cycles.
This study aimed to determine the precautions that can be taken to increase the reliability of the vestibular evoked myogenic potentials test without being affected by the asymmetry of the sternocleidomastoid muscle and the issues that should be considered in the interpretation of vestibular evoked myogenic potential results if these precautions are not taken.
Method
Individuals with sternocleidomastoid muscle activity of less than 30 μV in cervical vestibular evoked myogenic potential testing and an asymmetry ratio of more than 0.35 were excluded. In our study, individuals were divided into different groups according to sternocleidomastoid muscle asymetry.
Results
A total of 53 individuals were included in the study. Intergroup comparisons were made to determine the effect of electromyogram scaling and filter use on amplitude asymmetry ratio according to sternocleidomastoid muscle asymmetry.
Conclusion
Keeping the sternocleidomastoid muscle asymmetry not exceeding 10 μV maximises the reliability of cervical vestibular evoked myogenic potentials. As a result of our study, it can be concluded that in clinical applications the asymmetry should not exceed 20 μV.
The question of how translation can do justice is not about seeking equivalence but of acknowledging that translation is, following Spivak, insufficient but necessary nonetheless. I suggest that in asking what kind of justice translation might do, the term translation is carried across (trans-latio) from its technical or formal to its ethical-political dimensions, and the term justice is shifted from the terrain of the quest for parity or alikeness (eye for an eye) to the terrain of repair, dignity, care, responsibility, a justice on terms that are yet to be ascertained. This makes translation into a critical concept in theatre and performance, where, perhaps more than in any other art form, there is a systemic concern with how humans relate to each other and to non-human others.
A focus on care draws attention to the fact that ethical self-cultivation, even in traditions that foreground moral autonomy, relies upon relationships of dependence. The recognition of relational and ethical dependence is familiar to anthropologists and has long been central for feminist ethics. However, the enormous body of anthropological scholarship that has emerged on care over the last decade raises the question of ethical dependence anew. This chapter problematizes the concept of care. It asks: how might ‘care’ as a topic, and as engaged ethnographically, trouble some of the ways that ethical life more broadly has been conceived in the philosophical and anthropological literature? Conversely, how might attention to the ethical stakes of care trouble some of the rich ethnographic scholarship on care? The chapter draws most substantially on anthropological and philosophical scholarship in virtue ethics and in phenomenology to consider both the relational complexities of care and care’s ineffable and elusive ethical dimensions.
Harmful acts are punished more often and more harshly than harmful omissions. This asymmetry has variously been ascribed to differences in how individuals perceive the causal responsibility of acts versus omissions and to social norms that tend to proscribe acts more frequently than omissions. This paper examines both of these hypotheses, in conjunction with a new hypothesis: that acts are punished more than omissions because it is usually more efficient to do so. In typical settings, harms occur as a result of relatively few harmful actions, but many individuals may have had the opportunity to prevent or rectify the harm. Penalising actors therefore requires relatively few punishment events compared to punishing omitters. We employ a novel group paradigm in which harm occurs only if both actors and omitters contribute to the harm. Subjects play a repeated economic game in fixed groups involving a social dilemma (total N = 580): on each round self-interest favours harmful actions (taking from another) and harmful omissions (failing to repair the victim’s loss), but the group payoff is maximized if individuals refrain from these behaviors. In one treatment harm occurs as a result of one action and two omissions; in the other, it is the result of two actions and one omission. In the second treatment, the more efficient strategy to maximize group benefit is to punish omissions. We find that subjects continue to prefer to punish acts rather than omissions, with two important caveats. There is still a substantial level of punishment of omissions, and there is also evidence of some responsiveness to the opportunity to enforce a more efficient rule. Further analysis addresses whether the omission effect is associated with asymmetric norm-based attitudes: a substantial proportion of subjects regard it as equally fair to punish harmful acts and omissions, while another portion endorse an asymmetry; and punishment behavior correlates with these attitudes in both groups.
This article argues that although most Caribbean States have in the last 60 years ascended to statehood, colonialism continues to exist in new and variable forms. It relies upon the concept of ‘coloniality’ as advanced by Schneiderman to contend that the international investment law regime, whose history and evolution is rooted in colonialism, relentlessly pursues the economic interests of foreign investors and capital-exporting countries. It draws important connections between historic colonialism and the contemporary regime for the protection of foreign direct investment by situating the Caribbean's experience in the light of the rationales, tropes and methods arising in the past which endure in investment law's domains, as advanced by Schneiderman in his new book, Investment Law's Alibis, namely (a) profitability and privilege; (b) a discourse of improvement; (c) distrust of local self-rule; and (d) construction of legal enclaves. It is argued that each of these features of colonial rule, from a Caribbean perspective, is inscribed in the discourse and practices of the international investment law regime.
International organizations come in many shapes and sizes. Within this institutional gamut, the multipurpose multilateral intergovernmental organization (MMIGO) plays a central role. This institutional form is often traced to the creation of the League of Nations, but in fact the first MMIGO emerged in the Western Hemisphere at the close of the nineteenth century. Originally modeled on a single-issue European public international union, the Commercial Bureau of the American Republics evolved into the multipurpose, multilateral Pan American Union (PAU). Contrary to prominent explanations of institutional genesis, the PAU's design did not result from functional needs nor from the blueprints of a hegemonic power. Advancing a recent synthesis between historical and rational institutionalism, we argue that the first MMIGO arose through a process of compensatory layering: a mechanism whereby a sequence of bargains over control and scope leads to gradual but transformative institutional change. We expect compensatory layering to occur when an organization is focal, power asymmetries among members of that organization are large, and preferences over institutional design diverge. Our empirical and theoretical contributions demonstrate the value a more global international relations (IR) perspective can bring to the study of institutional design. international relations (IR) scholars have long noted that international organizations provide smaller states with voice opportunities; our account suggests those spaces may be of smaller states’ own making.
This study aimed to assess the incidence and severity of arytenoid adduction asymmetry in normophonic speakers and to identify related demographic characteristics.
Method
A retrospective observational clinical study on normophonic patients was conducted. Videos of flexible laryngoscopy of the study group (aged 18 to 45 years) were reviewed. Arytenoid adduction asymmetry, if present, was graded as mild (grade 1), moderate (grade 2) and severe (grade 3).
Results
Video recordings of 347 normophonic patients were analysed. The total prevalence of arytenoid adduction asymmetry was 36.4 per cent, with a predominance in males and on the right side. Right-sided predominance was statistically significant (p < 0.01). A total of 60.3 per cent of patients with arytenoid adduction asymmetry had only mild asymmetry, whereas 34.9 per cent had moderate asymmetry. Only 4.8 per cent showed severe asymmetry.
Conclusion
Arytenoid adduction asymmetry is found in more than one third of the normophonic population, has significant right-sided preponderance and was more common in males.
Regular patterns are common in living organisms. Examples are the radial symmetry of many flowers, the bilateral symmetry of most animals, the repetition of vertebrae or the branching of vascular systems. In principle, these regular patterns only require the repetition of one elementary module. There is no separate genetic control for each vertebra or body segment, or for left vs. right eyes. Deviation from symmetry, or from precise repetition of identical parts, may require specific control, as in the right- vs. left-handedness of gastropod shells, but what is controlled is deviation from symmetry, rather than polarity of handedness; therefore, flipping between directions can be easy. Repetition of a pattern at different scale produces fractal shapes of which there are a number in living nature. However, targeted investigation is required to confirm if a given symmetric or fractal pattern is produced in the mathematically simplest way, a prediction sometimes contradicted by facts. Genes are involved in specification of positions along the main body axis of animals, but the genome does not contain any specification of the linear paths along which nerve axons or fungal hyphae grow.
Fruit shape is the result of the interaction between genetic, epigenetic, environmental factors and stochastic processes. As a core biological descriptor both for taxonomy and horticulture, the point at which shape stability is reached becomes paramount in apple cultivar identification, and authentication in commerce. Twelve apple cultivars were sampled at regular intervals from anthesis to harvest over two growing seasons. Linear and geometric morphometrics were analysed to establish if and when shape stabilised and whether fruit asymmetry influenced this. Shape stability was detected in seven cultivars, four asymmetric and three symmetric. The remaining five did not stabilise. Shape stability, as defined here, is cultivar-dependent, and when it occurs, it is late in the growing season. Geometric morphometrics detected stability more readily than linear, especially in symmetric cultivars. Key shape features are important in apple marketing, giving the distinctness and apparent uniformity between cultivars expected at point of sale.
The abnormal animal featured here is the Shar-Pei dog, whose skin is severely rumpled. It turns out that the molecular basis for this abnormality is similar to that which causes the folding of the human brain. We go on to consider other "ripple" patterns (e.g., fingerprints) and why they're always asymmetric.