This study was carried out to determine the effects of different irrigation levels and different tillage and sowing methods on the amount of irrigation water, evapotranspiration, water productivity (WP) and yield in the second crop soybean in Çukurova Region, Turkey. Three irrigation levels were applied (I100: completion to the field capacity of the available water of 60 cm soil depth weekly. I70: 70% of the water applied to I100, I50: 50% of the water applied to I100), five tillage and sowing methods were used (T1: traditional soil tillage, T2: reduced soil tillage, T3: reduced soil tillage, T4: ridge tillage, T5: no-tillage). The research was carried out in a randomized block split-plot design with three replications. The result of, the highest yield was obtained in I100xT1 with 4990 kg/ha, while the lowest yield was obtained in I50xT3 with 3150 kg/ha in irrigation x tillage interactions. When the water consumption values of plants were analysed, the highest was obtained with 632 mm I100 and the lowest with 399 mm I50. When WP values were analysed, the highest was obtained with 8.7 in I50 and the lowest in 6.6 and I100. As a result, full irrigation and direct sowing methods (I100T1) are recommended in soybean cultivation considering the highest water-yield relationship in the Mediterranean Region.