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111 results

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  • Chapter 14 - Maimonides on Human Perfection and the Love of God

  • from Part VI - Human Ends
  • Edited by Daniel Frank, Purdue University, Indiana, Aaron Segal, Hebrew University of Jerusalem
  • Book: Maimonides' <I>Guide of the Perplexed</I>
  • Published online: 18 June 2021
  • Print publication: 01 July 2021, pp 266-285

  • Summary

    In this passage, we see Maimonides wrestling with a certain tension in his life: on the one hand, a devotion to his time-consuming obligations as a physician, to healing the sick among the wealthy and the poor; on the other hand, his personal desire for the opportunity to engage in the study of Torah and other religious and philosophical texts. He is torn between two competing values: the life of practical activity and the life of contemplation.

  • Scale-up of the Accrual to Clinical Trials (ACT) network across the Clinical and Translational Science Award Consortium: a mixed-methods evaluation of the first 18 months

  • Elaine H. Morrato, Lindsay A. Lennox, Elaina R. Sendro, Anne L. Schuster, Harold A. Pincus, Jennifer Humensky, Gary S. Firestein, Lee M. Nadler, Robert Toto, Steven E. Reis
  • Journal: Journal of Clinical and Translational Science / Volume 4 / Issue 6 / December 2020
  • Published online by Cambridge University Press: 30 June 2020, pp. 515-528
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  • Introduction:

    The Clinical and Translational Science Award (CTSA) Program is a Consortium of nearly 60 academic medical research centers across the USA and a natural network for evaluating the spread and uptake of translational research innovation across the Consortium.

    Methods:

    Dissemination of the Accrual to Clinical Trials (ACT) Network, a federated clinical informatics data network for population-based cohort discovery, began January 2018 across the Consortium. Diffusion of innovation theory guided dissemination design and evaluation. Mixed-methods assessed the spread and uptake across the Consortium through July 1, 2019 (n = 48 CTSAs). Methods included prospective time activity tracking (Kaplan–Meier curves), and survey and qualitative interviews.

    Results:

    Within 18 months, nearly 80% of CTSAs had joined the data network and two-thirds of CTSAs achieving technical readiness had initiated launch to local clinical investigators. Over 10,000 ACT Network queries are projected for 2019; and by 2020, nearly all CTSAs will have joined the network. Median time-from-technical-readiness-to-local-launch was 154 days (interquartile range: 87–225 days]. Quality improvement processes reduced time-to-launch by 35.2% (64 days, p = 0.0036). Lessons learned include: (1) conceptualize dissemination as two-stage adoption demonstrating value for both CTSA hub service providers and clinical investigators; (2) include institutional trial into dissemination strategies so CTSA hubs can refine internal workflows and gather local user feedback endorsement; (3) embrace designing-for-dissemination during technology development; and (4) sustain adaptive dissemination and customer relationship management to keep CTSA hubs and users engaged.

    Conclusions:

    Scale-up and spread of the ACT Network provides lessons learned for others disseminating innovation across the CTSA Consortium. The Network is primed for embedded implementation research.

  • Berkeley's Ideas and the Primary/Secondary Distinction

  • Steven Nadler
  • Journal: Canadian Journal of Philosophy / Volume 20 / Issue 1 / March 1990
  • Published online by Cambridge University Press: 01 January 2020, pp. 47-61

  • Part of Berkeley's strategy in his attack on materialism in the Three Dialogues Between Hylas and Philonous is to argue that the epistemological distinction between ideas of so-called primary qualities and ideas of secondary qualities, especially as this distinction is found in Locke, is untenable. Both kinds of ideas-those presenting to the mind the quantifiable properties of bodies (shape, size, extension, motion) and those which are just sensations (color, odor, taste, heat)-are equally perceptions in the mind, and there is no reason to believe that one kind (the ideas of primary qualities) represents true properties of independently existing external objects while the other kind does not.

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