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XYY Males: Some Clinical and Psychiatric Aspects Deriving from a Survey of 1,811 Males in Hospitals for the Mentally Handicapped

  • Henry Hunter (a1)

Abstract

A survey of 1,811 mentally handicapped males in eighteen hospitals is described. Males discovered with supernumerary Y chromosomes numbered 15, of whom 12 were 47,XYY. Some of the physical, social, psychological and psychiatric findings are described and compared with groups matched for IQ and height.

The main psychiatric findings are diminished intelligence, retardation in development of secondary sexual characteristics, and poor emotional control leading to inadequate social adaptive patterns which are described and discussed.

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1 Aitken, J., Brunton, M., Jacobs, P. A., Price, W. H. & MacColl, K. (1971) Chromosome studies on male patients at a mental subnormality hospital. Clinical Genetics, 2, 338–45.
2 Buckton, K. E., Bond, J. A. & McBridge, J. A. (1962) An XYY sex chromosome complement in a male with hypogonadism. Human Chromosome Newsletter, No. 8, 11.
3 Casey, M. D., Segal, L. J., Street, D. R. K. & Blank, C. E. (1966) Sex chromosome abnormalities in two state hospitals for patients requiring special security. Nature, 5023, 641–2.
4 Casey, M. D., Blank, C. E., Mobley, T., Kohn, P., Street, D. R. K., McDougall, J. H., Gooder, J. & Platts, J. (1971) Special Hospitals Research Report, No. 2, p 3.
5 Court Brown, W. M. (1968) Male with an XYY sex chromosome complement. J. Med. Genet., 5, 341.
6 Court Brown, W. M., Harnden, D. G., Jacobs, P. A., Maclean, N. & Mantle, D. J. (1964) Abnormalities of the sex chromosome complement in man. M.R.C. Special Report 305. HMSO.
7 Fraccaro, M., Glen Bott, M., Davies, P. & Schutt, (1962) Mental deficiency and undescended testes in two males with XYY chromosomes. Folia hered. Path., 11, 211.
8 Hook, Ernest B. (1973) Behavioural implication of human XYY genotype. Science, 179, 139–50.
9 Hunter, H. (1966) YY chromosomes in Klinefelter's syndrome. Lancet, i, 984.
10 Hunter, H. (1967) Some clinical observation on Klinefelter's syndrome in a subnormal population in England. M.D. Thesis, Univ. of London.
11 Hunter, H. (1968) Chromatin positive and XYY boys in approved schools. Lancet, i, 816.
12 Hunter, H. & Quaife, R. (1973) A 48,XYYY male—a somatic and psychiatric description. J. of Med. Genet., 10(1), 80–3.
13 Jacobs, P. A., Price, W. H., Brown, W. M. C., Brittain, R. P. & Whatmore, P. B. (1968) Chromosome studies on men in a maximum security hospital. Ann. Hum. Genet., 31, 339–58.
14 Kinsey, A. C., Pomeron, W. B. & Martin, C. E. (1948) Sexual Behavior in the Human Male. Philadelphia: W. B. Saunders & Co.
15 Milou, St. M., Negoesou, I., Garoiu, M., Iuesou, I., Auoustin, M. & Maximilian, C. (1963) An XYY sex chromosome complement in a male with hypospadias. Human Chromosome Newsletter, No. 9.
16 Moorhead, P. S., Nowell, P. C., Mellman, W. J., Battips, D. M. & Hungerford, D. A. (1960) Chromosome preparation of leucocytes cultures from human peripheral blood. Experimental Cell Research, 20, 613–16.
17 Newton, M. S., Jacobs, P. A., Price, W. H., Woodcock, G. & Frazer, I. A. (1972) A chromosome survey of a hospital for the mentally subnormal. Clinical Genetics, 3, 215–55.
18 Pearson, P. L. & Bobrow, M. (1970) Technique for identifying Y chromosome in human interphase nuclei. Nature, 1, 226.
19 Penrose, L. E. (1970) The contribution of cytogenetics to clinical psychology. In Modern Trends in Psychological Medicine, 2 (ed. Hill, O. W.). London: Butterworth
20 Price, W. H. & Whatmore, P. B. (1967) Behaviour disorders and patterns of crime among XYY males identified at a maximum security hospital. British Medical Journal, i, 533–6.
21 Price, W. H. (1968) The electrocardiogram in males with extra Y chromosomes. Lancet, i, 1106.
22 Ratcliffe, G. S., Stewart, L. A., Melville, M. M., Jacobs, P. A. & Keay, A. J. (1970) Chromsome studies on 3,500 newborn male infants. Lancet, i, 121–2.
23 Rica, N. & Malacarne, P. (1964) An XYY human male. Lancet, i, 7335.
24 Sandberg, A. A., Keopf, G. F., Ishihara, Y. & Hauschka, T. A. (1961) An XYY human male. Lancet, ii, 488–9.
25 Sandberg, A. A., Ishihara, T., Crosswhite, L. H. & Keopf, G. F. (1963) XYY genotype: report of a case in a male. New Engl. J. Med., 268, ii.
26 Vignetti, P., Capotorti, L. & Ferrante, E. (1964) XYY chromosomal constitution with genital abnormality. Lancet, ii, 7359.

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XYY Males: Some Clinical and Psychiatric Aspects Deriving from a Survey of 1,811 Males in Hospitals for the Mentally Handicapped

  • Henry Hunter (a1)
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