Skip to main content Accessibility help
×
Home

Usefulness of Saliva Lithium Estimation

  • Abraham Verghese (a1), N. Indrani (a1), K. Kuruvilla (a1) and Peter G. Hill (a1)

Summary

Estimation of lithium in 24 samples of serum and saliva show that there is a very high correlation between the lithium levels in serum and saliva (r= +0·88). The ratio found in our patients is very similar to that reported from North America. Estimation of lithium in saliva at different periods of time show there is a good degree of stability for saliva lithium levels. Thus saliva can be used as a substitute for serum for lithium monitoring. The practical advantages of this are discussed.

Copyright

References

Hide All
Angst, J. & Weis, P. (1970) Lithium prophylaxis in recurrent affective disorders. British Journal of Psychiatry, 116, 604–14.
Baastrup, P. (1964) The use of lithium in manic-depressive psychosis. Comprehensive Psychiatry, 5, 396408.
Baastrup, P. (1970) Prophylactic lithium: double blind discontinuation in manic depressive and recurrent depressive disorders. Lancet, ii, 326–30.
Brown, P. B. & Leo, E. F. (1970) The estimation of lithium in serum. Annals of Clinical Biochemistry, 7, 1315.
Coppen, A., Noguera, R., Bailey, J., Burns, B. H., Swani, M. S., Hare, E. H., Gardner, R. & Maggs, R. (1971) Prophylactic lithium in affective disorder. Lancet, ii, 375–9.
Gershon, S. (1968) The use of lithium salts in psychiatric disorders. Diseases of the Nervous System, 29, 51–5.
Hullin, R. P., McDonald, R. & Allsopp, M. N. E. (1972) Prophylactic lithium in recurrent affective disorders. Lancet, i, 1044–6.
Mendels, J., Secunda, S. K. & Dyson, W. L. (1972) A controlled study of the antidepressant effects of lithium carbonate. Archives of General Psychiatry, 26, 154–7.
Neu, C., Dimascio, A. & Williams, D. (1975) Saliva lithium levels: clinical applications. American Journal of Psychiatry, 132, 66–8.
Shopsin, B., Gershon, S. & Pinckney, L. (1969) The secretion of lithium in human mixed saliva; effects of ingested lithium on electrolyte distribution in saliva and serum. International Pharmaco-psychiatry, 2, 148–69.
Spring, K. R. & Spirtes, M. A. (1969) Salivary excretion of lithium: human parotid and submaxillary secretions. Journal of Dental Research, 48, 546–9.

Usefulness of Saliva Lithium Estimation

  • Abraham Verghese (a1), N. Indrani (a1), K. Kuruvilla (a1) and Peter G. Hill (a1)

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed.

Usefulness of Saliva Lithium Estimation

  • Abraham Verghese (a1), N. Indrani (a1), K. Kuruvilla (a1) and Peter G. Hill (a1)
Submit a response

eLetters

No eLetters have been published for this article.

×

Reply to: Submit a response


Your details


Conflicting interests

Do you have any conflicting interests? *