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Predicting onset of bipolar disorder from subsyndromal symptoms: a signal question?

  • Gordon Parker (a1)

Summary

This issue reports a community-based study quantifying the extent to which subthreshold hypomanic or depressive symptoms in childhood or adolescence predicted subsequent formal bipolar disorder status and mental health service attendance. This editorial emphasises the low predictive power of the signal and considers early intervention implications.

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References

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1 Tijssen, MJA, van Os, J, Wittchen, H-U, Lieb, R, Beesdo, K, Mengelers, R, et al. Prediction of transition from common adolescent bipolar experiences to bipolar disorder: 10-year study. Br J Psychiatry 2010; 196: 102108.
2 Hadjipavlou, G, Yatham, LN. Bipolar II disorder in context: epidemiology, disability and economic burden. In Bipolar II Disorder: Modelling, Measuring and Managing (ed Parker, G): 6174. Cambridge University Press, 2008.
3 Chang, K. Adult bipolar disorder is continuous with pediatric bipolar disorder. Can J Psychiatry 2007; 52: 418–25.
4 Youngstrom, EA, Birmaher, B, Findling, RL. Pediatric bipolar disorder: validity, phenomenology, and recommendations for diagnosis. Bipolar Disord 2008; 10: 194214.
5 Moreno, C, Laje, G, Blanco, C, Jiang, H, Schmidt, AB, Olfson, M. National trends in the outpatient diagnosis and treatment of bipolar disorder in youth. Arch Gen Psych 2007; 64: 1032–9.
6 Sartorius, N, Schulze, H. Reducing the Stigma of Mental Illness: A Report from a Global Programme of the World Psychiatric Association. Cambridge University Press, 2005.

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Predicting onset of bipolar disorder from subsyndromal symptoms: a signal question?

  • Gordon Parker (a1)
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