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Long-term course of acute brief psychosis in a developing country setting

  • Ezra Susser (a1), Vijoy K. Varma (a2), S. K. Mattoo (a2), Molly Finnerty (a1), Ramin Mojtabai (a1), B. M. Tripathi (a2), Arun K. Misra (a2) and N. N. Wig (a2)...



This study in North India compared acute brief psychosis – defined by acute onset, brief duration and no early relapse – with other remitting psychoses, over a 12-year course and outcome.


In a cohort of incident psychoses, we identified 20 cases of acute brief psychosis and a comparison group of 43 other remitting psychoses based on two-year follow-up. Seventeen people (85%) in the acute brief psychosis group and 36 (84%) in the comparison group were reassessed at five, seven and 12 years after onset, and were rediagnosed using ICD–10 criteria.


At 12-year follow-up, the proportion with remaining signs of illness was 6% (n=1) for acute brief psychosis versus 50% (n=18) for the comparison group (P=0.002). Using ICD–10 criteria, the majority in both groups were diagnosed as having schizophrenia.


Acute brief psychosis has a distinctive and benign long-term course when compared with other remitting psychoses. This finding supports the ICD– 10 concept of a separable group of acute and transient psychotic disorders. To effectively separate this group, however, the ICD–10 criteria need modification.


Corresponding author

Ezra Susser, Box 24, New York State Psychiatric Institute, 722 West 168 Street, New York, NY 10032, USA. Tel: 212-740-6316. Fax: 212-795-9768. E-mail:


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Long-term course of acute brief psychosis in a developing country setting

  • Ezra Susser (a1), Vijoy K. Varma (a2), S. K. Mattoo (a2), Molly Finnerty (a1), Ramin Mojtabai (a1), B. M. Tripathi (a2), Arun K. Misra (a2) and N. N. Wig (a2)...


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Long-term course of acute brief psychosis in a developing country setting

  • Ezra Susser (a1), Vijoy K. Varma (a2), S. K. Mattoo (a2), Molly Finnerty (a1), Ramin Mojtabai (a1), B. M. Tripathi (a2), Arun K. Misra (a2) and N. N. Wig (a2)...
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