Alexopoulos, GS. Depression in the elderly.
2005; 365: 1961–70.
Unutzer, J. Diagnosis and treatment of older adults with
depression in primary care. Biol
2002; 52: 285–92.
Tiemeier, H, Breteler, MM, Hofman, A, Stijnen, T. A multivariate score objectively assessed health of
depressed elderly. J Clin Epidemiol
2005; 58: 1134–41.
Penninx, BW, Geerlings, SW, Deeg, DJ, van Eijk, JT, van Tilburg, W, Beekman, AT. Minor and major depression and the risk of death in
older persons. Arch Gen Psychiatry
1999; 56: 889–95.
Schulz, R, Beach, SR, Ives, DG, Martire, LM, Ariyo, AA, Kop, WJ. Association between depression and mortality in
older adults: the Cardiovascular Health Study.
Arch Intern Med
2000; 160: 1761–8.
Anstey, KJ, Luszcz, MA. Mortality risk varies according to gender and change
in depressive status in very old adults.
2002; 64: 880–8.
Vinkers, DJ, Stek, ML, Gussekloo, J, Mast, RC van der, Westendorp, RG. Does depression in old age increase only
cardiovascular mortality? The Leiden 85-plus Study.
Int J Geriatr Psychiatry
2004; 19: 852–7.
Adamson, JA, Price, GM, Breeze, E, Bulpitt, CJ, Fletcher, AE. Are older people dying of depression? Findings from
the Medical Research Council trial of the assessment and management of
older people in the community. J Am Geriatr
2005; 53: 1128–32.
Thomas, C, Kelman, HR, Kennedy, GJ, Ahn, C, Yang, C. Depressive symptoms and mortality in elderly
persons. J Gerontol
Callahan, CM, Wolinsky, FD, Stump, TE, Nienaber, NA, Hui, SL, Tierney, WM. Mortality, symptoms, and functional impairment in
late-life depression. J Gen Intern Med
1998; 13: 746–52.
Cuijpers, P. Mortality and depressive symptoms in inhabitants of
residential homes. Int J Geriatr
2001; 16: 131–8.
Hybels, CF, Pieper, CF, Blazer, DG. Sex differences in the relationship between
subthreshold depression and mortality in a community sample of older
adults. Am J Geriatr Psychiatry
2002; 10: 283–91.
McCusker, J, Cole, M, Ciampi, A, Latimer, A, Windholz, S. Does depression in older medical inpatients predict
J Gerontol A Biol Sci Med Sci
2006; 61: 975–81.
Blazer, DG, Hybels, CF, Pieper, CF. The association of depression and mortality in
elderly persons: a case for multiple, independent
pathways. J Gerontol Biol Sci Med Sci
2001; 56: M505–9.
The 3C Study Group. Vascular factors and
risk of dementia: design of the three city study and baseline
characteristics of the study population.
2003; 22: 316–25.
Sheehan, DV, Lecrubier, Y, Sheehan, KH, Amorim, P, Janavs, J, Weiller, E, Hergueta, T, Baker, R, Dunbar, GC. The Mini-International Neuropsychiatric Interview
(MINI): the development and validation of a structured diagnostic
psychiatric interview for DSM-IV and ICD-10. J
Suppl 20: 22–33;
American Psychiatric Association. Diagnostic and
Statistical Manual of Mental Disorders (4th
Radloff, LS. The CES-D scale: a self-report depression scale for
research in the general population. Appl Psychol
World Health Organization. World Health Organising
Collaborating Centre for Drug Statistics Methodology. Guidelines for ATC
Classification and DDD assignment.
World Health Organization. International
Statistical Classification of Diseases and Related Health
Lawton, MP, Brody, EM. Assessment of older people: self-maintaining and
instrumental activities of daily living.
1969; 9: 179–86.
Katz, S, Ford, AB, Moskowitz, RW, Jackson, BA, Jaffe, MW. Studies of illness in the aged. The index of adl: a
standardised measure of biological and psychosocial
1963; 185: 914–19.
Folstein, MF, Folstein, SE, McHugh, PR. “Mini-mental state.” A practical method for grading
the cognitive state of patients for the clinician.
J Psychiatr Res
1975; 12: 189–98.
Commenges, D, Letenneur, L, Joly, P, Alioum, A, Dartigues, JF. Modelling age-specific risk: application to
dementia. Stat Med
1998; 17: 1973–88.
Wulsin, LR, Evans, JC, Vasan, RS, Murabito, JM, Kelly-Hayes, M, Benjamin, EJ. Depressive symptoms, coronary heart disease, and
overall mortality in the Framingham Heart Study.
Kornstein, SG, Sloan, DM, Thase, ME. Gender-specific differences in depression and
treatment response. Psychopharmacol Bull
Crawford, MJ, Prince, M, Menezes, P, Mann, AH. The recognition and treatment of depression in older
people in primary care. Int J Geriatr
1998; 13: 172–6.
Gorman, JM. Gender differences in depression and response to
psychotropic medication. Gend Med
Khan, A, Brodhead, AE, Schwartz, KA, Kolts, RL, Brown, WA. Sex differences in antidepressant response in recent
antidepressant clinical trials. J Clin
2005; 25: 318–24.
Cohen, HW, Gibson, G, Alderman, MH. Excess risk of myocardial infarction in patients
treated with antidepressant medications: association with use of
tricyclic agents. Am J Med
Van Rijswijk, E, Borghuis, M, van de Lisdonk, E, Ziman, F, Van Weel, C. Treatment of mental health problems in general
practice: a survey of psychotropics prescribed and other treatments
provided. Int J Clin Pharmacol Ther
2007; 45: 23–9.
Stek, ML, Vinkers, DJ, Gussekloo, J, Beekman, ATF, van der Mast, RC, Westendorp, RG. Is depression in old age fatal only when people feel
Am J Psychiatry
2005; 162: 178–80.
Ciechanowski, PS, Katon, WJ, Russo, JE. Depression and diabetes: impact of depressive
symptoms on adherence, function, and costs. Arch
2000; 160: 3278–85.
Kivimaki, M, Gunnell, D, Lawlor, DA, Davey Smith, G, Pentti, J, Virtanen, M, Elovainio, M, Klaukka, T, Vahtera, J. Social inequalities in antidepressant treatment and
mortality: a longitudinal register study. Psychol