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Fasting Blood Lipid Concentrations in Manic-Depressive Psychosis

Published online by Cambridge University Press:  29 January 2018

R. P. Hullin
Affiliation:
University of Leeds, and Director, Metabolic Research Unit, High Royds Hospital, Menston, Ilkley, Yorkshire
G. Court
Affiliation:
Department of Biochemistry, University of Leeds

Extract

Human blood plasma normally contains 500–1,000 mg./100 ml. of lipid material kept in solution by complex formation in various proportions with protein to form lipoproteins of definite size and constitution. Apart from the chylomicrons at least four β-lipoproteins and two α-lipoproteins are recognized, differing from each other in density. The α-lipoproteins correspond to the α-globulins and the β-lipoproteins to the β-globulins as determined by paper electrophoresis. The various lipoproteins have been shown to possess a constant and characteristic pattern both in protein: lipid ratio and in the relative proportions of phospholipid, sterol, sterol esters and glycerides (Jones et al, 1951; Bragdon et al., 1956). The proportions in which the fatty acids are present have also been shown to be constant (Lindgren et al., 1959).

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1970 

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