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Cosegregation of Christmas Disease and Major Affective Disorder in a Pedigree

Published online by Cambridge University Press:  02 January 2018

Michael Gill*
Affiliation:
Institute of Psychiatry, DeCrespigny Park, London SE5 8AF
David Castle
Affiliation:
Institute of Psychiatry, London
Conor Duggan
Affiliation:
Institute of Psychiatry, London
*
Correspondence

Abstract

Three males with factor-IX deficiency (Christmas disease) in one pedigree all had severe affective disorder. This apparent cosegregation, if true, would support the hypothesis that in some pedigrees, a gene for major affective disorder is located on the X chromosome.

Type
Brief Reports
Copyright
Copyright © The Royal College of Psychiatrists 

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