Hostname: page-component-78c5997874-xbtfd Total loading time: 0 Render date: 2024-11-18T08:42:45.677Z Has data issue: false hasContentIssue false

Comparison of the Prophylactic Action of Flupenthixol with Placebo in Lithium Treated Manic-Depressive Patients

Published online by Cambridge University Press:  29 January 2018

J. Esparon
Affiliation:
Murray Royal Hospital, Perth
J. Kolloori
Affiliation:
Royal Dundee Liff Hospital
G. J. Naylor*
Affiliation:
Royal Dundee Liff Hospital, Dundee DD2 51F
A. M. McHarg
Affiliation:
Royal Dundee Liff Hospital
A. H. W. Smith
Affiliation:
Royal Dundee Liff Hospital
S. E. Hopwood
Affiliation:
Royal Dundee Liff Hospital
*
Correspondence

Abstract

A double-blind cross-over trial of depot flupenthixol in recurrent manic depressive psychosis was carried out. Ail patients continued on lithium. Eleven patients completed the two-year trial. Flupenthixol appeared to have no prophylactic effect.

Type
Brief Reports
Copyright
Copyright © 1986 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Ahlpors, U. G., Baastrup, P. C., Dencker, S. J., Elgen, K., Lingjafrde, O., Pedersen, V., Schou, M. & Aaskoven, O. (1981) Flupenthixol decanoate in recurrent manic depressive illness. A comparison with lithium. Acta Psychiatrica Scandinavica, 64, 226237.Google Scholar
Coppen, A., Montgomery, S. A., Gupta, R. K. & Bailey, J. E. (1976) A double blind comparison of lithium carbonate and Maprotiline in the prophylaxis of the affective disorders. British Journal of Psychiatry, 128, 479485.Google Scholar
Coppen, A., Abou-Saleh, M., Milln, P., Bailey, J. & Wood, K. (1984) Decreasing lithium dosage reduces morbidity and side effects during prophylaxis. Journal of Affective Disorders, 6, 353362.Google Scholar
Naylor, G. & Scott, C. (1980) Depot injections for affective disorders. British Journal of Psychiatry, 136, 105.Google Scholar
Reiter, P. (1969) On flupenthixol, an antidepressant of a new chemical group. British Journal of Psychiatry, 115, 13991402.Google Scholar
Sonne, L. M. (1966) Behandling af depressive tilstande med flupenthixol. Nordisk Psychiatrisk Tiddskrift. 20, 322324.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.