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Statin prescription and dietary imprudence

Published online by Cambridge University Press:  12 April 2013

S. F. McAleer
Affiliation:
Dept of General Practice and Primary Care, Queen's University Belfast, Belfast, UK, BT9 7HR
C. E. Neville
Affiliation:
Dept of General Practice and Primary Care, Queen's University Belfast, Belfast, UK, BT9 7HR
M. C. McKinley
Affiliation:
Centre for Public Health, Queen's University Belfast, Belfast, UK, BT12 6BJ UKCRC Centre of Excellence for Public Health (NI), Belfast, BT12 6BJ, UK
J. V. Woodside
Affiliation:
Centre for Public Health, Queen's University Belfast, Belfast, UK, BT12 6BJ UKCRC Centre of Excellence for Public Health (NI), Belfast, BT12 6BJ, UK
M. A. Tully
Affiliation:
Dept of General Practice and Primary Care, Queen's University Belfast, Belfast, UK, BT9 7HR Centre for Public Health, Queen's University Belfast, Belfast, UK, BT12 6BJ UKCRC Centre of Excellence for Public Health (NI), Belfast, BT12 6BJ, UK
M. E. Cupples
Affiliation:
Dept of General Practice and Primary Care, Queen's University Belfast, Belfast, UK, BT9 7HR Centre for Public Health, Queen's University Belfast, Belfast, UK, BT12 6BJ UKCRC Centre of Excellence for Public Health (NI), Belfast, BT12 6BJ, UK
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Abstract

Type
Abstract
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Copyright © The Authors 2013

In efforts to obtain optimal control of serum cholesterol, statin prescriptions have increased exponentially over the past 10 years in the UK( Reference Tonelli, Lloyd and Clement 1 ). NICE guidelines recommend that statin prescription should be accompanied by the delivery of advice to follow a healthy diet, but little is known about reported lifestyle behaviour changes after statin prescription. This study examined reported changes in diet following initiation of statin therapy in a UK primary care population.

Twelve general practices were selected in greater Belfast and all agreed to participate. Over a four month period, eligible patients were selected using a specified search strategy, these being those who were fully registered in the practices, aged >18 y, given a prescription for a statin medication and with no history of statin use. Following informed consent, each participant was posted a 4-day food diary and, 72–96 hours later, were contacted by telephone to confirm their eligibility, ask questions about their smoking habit, lifestyle advice received, recent changes in diet and past medical history( Reference Roe, Strong and Whiteside 2 ). This initial contact was timed to take place four weeks after their first prescription was issued (Month 1). Three months later a second food diary was posted and the telephone questionnaire was repeated (Month 4). Food diaries were analysed using the Weighed Intake Software Programme (WISP© version 3.0, Tinuviel Software, Warrington, UK). Ethical approval was obtained from the School of Medicine and Dentistry Research Ethics Committee, Queen's University Belfast. Paired t-tests were used to examine changes in dietary intake between Month 1 and Month 4.

Following a single mailing, 122 of 384 (32%) potentially eligible participants responded, with n 109 participants completing both telephone questionnaires and n 92 participants completing both food diaries. No significant changes in dietary intake were evident between the two time points, although there was a trend towards a reduction in saturated fat (P=0.09) and an increase in polyunsaturated fat (P=0.06).

a P value for difference between month 1 and month 4 using paired samples t-test.

From this study, statin prescription in the UK is not associated with significant dietary improvement, suggesting that an increased emphasis on the importance of diet is needed in consultations between healthcare professionals and patients.

References

1. Tonelli, M, Lloyd, A, Clement, F et al. (2011) CMAJ 183, 11891202.CrossRefGoogle Scholar
2. Roe, L, Strong, C, Whiteside, C et al. (1994) Fam Pract 11, 375381.CrossRefGoogle Scholar

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