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Immunity to Hymenolepis diminuta: unresponsiveness of the athymic nude mouse to infection

Published online by Cambridge University Press:  06 April 2009

P. W. Bland
P. W. Bland
Affiliation:
Wellcome Laboratories for Experimental Parasitology, University of Glasgow, Bearsden Road, Glasgow, G61
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Summary

Male and female congenitally athymic nude (nu/nu) mice infected with a single cysticercoid of Hymenolepis diminuta at 6 weeks of age retain the infection for at least 33 days. In the males of their phenotypically normal litter-mates, however, a single cysticercoid infection establishes and grows but is expelled between days 11 and 17. The unresponsiveness of the nude mouse to single H. diminuta infection is evidence that the immune rejection from normal mice is thymus-dependent.

Type
Research Article
Information
Parasitology , Volume 72 , Issue 1 , February 1976 , pp. 93 - 97
Copyright
Copyright © Cambridge University Press 1976

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References

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