Skip to main content Accessibility help
×
Home

Evaluation of the impact of 2 years of a dosing intervention on canine echinococcosis in the Alay Valley, Kyrgyzstan

  • F. VAN KESTEREN (a1) (a2), A. MASTIN (a1), P. R. TORGERSON (a3), BERMET MYTYNOVA (a4) and P. S. CRAIG (a1)...

Summary

Echinococcosis is a re-emerging zoonotic disease in Kyrgyzstan. In 2012, an echinococcosis control scheme was started that included dosing owned dogs in the Alay Valley, Kyrgyzstan with praziquantel. Control programmes require large investments of money and resources; as such it is important to evaluate how well these are meeting their targets. However, problems associated with echinococcosis control schemes include remoteness and semi-nomadic customs of affected communities, and lack of resources. These same problems apply to control scheme evaluations, and quick and easy assessment tools are highly desirable. Lot quality assurance sampling was used to assess the impact of approximately 2 years of echinococcosis control in the Alay valley. A pre-intervention coproELISA prevalence was established, and a 75% threshold for dosing compliance was set based on previous studies. Ten communities were visited in 2013 and 2014, with 18–21 dogs sampled per community, and questionnaires administered to dog owners. After 21 months of control efforts, 8/10 communities showed evidence of reaching the 75% praziquantel dosing target, although only 3/10 showed evidence of a reduction in coproELISA prevalence. This is understandable, since years of sustained control are required to effectively control echinococcosis, and efforts in the Alay valley should be and are being continued.

Copyright

Corresponding author

*Corresponding author: Department of Psychology, University of Michigan, 530 Church Street Ann Arbor, MI 48109, USA. E-mail: freyavankesteren@gmail.com

References

Hide All
Allan, J. C. and Craig, P. S. (2006). Coproantigens in taeniasis and echinococcosis. Parasitology International 55, S75S80.
Allan, J. C., Craig, P. S., Garcia Noval, J., Mencos, F., Liu, D., Wang, Y., Wen, H., Zhou, P., Stringer, R., Rogan, M. T. and Zeyhle, E. (1992). Coproantigen detection for immunodiagnosis of echinococcosis and taeniasis in dogs and humans. Parasitology 104, 347355.
Alvares Rojas, C. A., Romig, T. and Lightowlers, M. W. (2014). Echinococcus granulosus sensu lato genotypes infecting humans – review of current knowledge. International Journal for Parasitology 44, 918.
Benner, C., Carabin, H., Sánchez-Serrano, L. P., Budke, C. M. and Carmena, D. (2010). Analysis of the economic impact of cystic echinococcosis in Spain. Bulletin of the World Health Organization 88, 4957.
Bobek, B. (1969). Survival, turnover and production of small rodents in a beech forest. Acta Theriologica 14, 191210.
Craig, P. S. and Larrieu, E. (2006). Control of cystic echinococcosis/hydatidosis: 1863–2002. Advances in Parasitology 61, 443508.
Craig, P. S., Gasser, R. B., Parada, L., Cabrera, P., Parietti, S., Borgues, C., Acuttis, A., Agulla, J., Snowden, K. and Paolillo, E. (1995). Diagnosis of canine echinococcosis: comparison of coproantigen and serum antibody tests with arecoline purgation in Uruguay. Veterinary Parasitology 56, 293301.
Craig, P. S., Budke, C., Schantz, P. M., Li, T., Qiu, J., Yang, Y., Zehyle, E., Rogan, M. T. and Ito, A. (2007). Human echinococcosis – a neglected disease? Tropical Medicine and Health 35, 283292.
Craig, P. S., Mastin, A., van Kesteren, F. and Boufana, B. (2015). Echinococcus granulosus: epidemiology and state-of-the-art of diagnostics in animals. Veterinary Parasitology 213, 132148.
Devevey, G. and Christe, P. (2009). Flea infestation reduces the life span of the common vole. Parasitology 136, 13511355.
Dodge, H. F. and Romig, H. G. (1929). A method of sampling inspection. The Bell System Technical Journal 8, 613631.
Eckert, J. and Deplazes, P. (2004). Biological, epidemiological, and clinical aspects of echinococcosis, a zoonosis of increasing concern. Clinical Microbiology Reviews 17, 107135.
Fujikura, T. (1991). Growing importance of prevention and control of alveolar echinococcosis. World Health Forum 12, 146150.
Gardner, I. A. and Greiner, M. (2006). Receiver-operating characteristic curves and likelihood ratios: improvements over traditional methods for the evaluation and application of veterinary clinical pathology tests. Veterinary Clinical Pathology 35, 817.
Gemmell, M. A., Lawson, J. R. and Roberts, M. G. (1986). Control of echinococcosis/hydatidosis: present status of worldwide progress. Bulletin of the World Health Organization 64, 333339.
Lembo, T., Craig, P. S., Miles, M. A., Hampson, K. R. and Meslin, F. X. (2013). Zoonoses prevention, control, and elimination in dogs. In Dogs, Zoonoses and Public Health (ed. Macpherson, C. N. L., Meslin, F. X. and Wandeler, A. I.), pp. 205259. CABI, Wallingford, UK.
Lemeshow, S. and Taber, S. (1991). Lot quality assurance sampling: single and double sampling plans. World Health Statistics Quarterly 44, 115132.
Mastin, A. (2015). Canine echinococcosis in Kyrgyzstan: detection, diagnosis, and dynamics. Ph.D. School of Environment and Life Sciences. University of Salford, Salford, UK.
Mastin, A., van Kesteren, F., Torgerson, P. R., Ziadinov, I., Mytynova, B., Rogan, M. T., Tursunov, T. and Craig, P. S. (2015). Risk factors for Echinococcus coproantigen positivity in dogs from the Alay valley, Kyrgyzstan. Journal of Helminthology 89, 655663.
Moro, P. and Schantz, P. M. (2009). Echinococcosis: a review. International Journal of Infectious Diseases 13, 125133.
Moss, J. E., Chen, X., Li, T., Qiu, J., Wang, Q., Giraudoux, P., Ito, A., Torgerson, P. R. and Craig, P. S. (2013). Reinfection studies of canine echinococcosis and role of dogs in transmission of Echinococcus multilocularis in Tibetan communities, Sichuan, China. Parasitology 140, 16851692.
Pierangeli, N. B., Soriano, S. V., Roccia, I., Bergagna, H. F. J., Lazzarini, L. E., Celescinco, A., Kossman, A. V., Saiz, M. S. and Basualdo, J. A. (2010). Usefulness and validation of a coproantigen test for dog echinococcosis screening in the consolidation phase of hydatid control in Neuquén, Argentina. Parasitology International 59, 394399.
Raimkylov, K. M., Kuttubaev, O. T. and Toigombaeva, V. S. (2015). Epidemiological analysis of the distribution of cystic and alveolar echinococcosis in Osh Oblast in the Kyrgyz Republic, 2000–2013. Journal of Helminthology 89, 651654.
Robertson, S. E. and Valadez, J. J. (2006). Global review of health care surveys using lot quality assurance sampling (LQAS), 1984–2004. Social Science and Medicine 63, 16481660.
Schantz, P. M. (1997). Sources and use of surveillance data for cystic echinococcosis. In Compendium on Cystic Echinococcosis in Africa and in Middle Eastern Countries with Special Reference to Morocco (ed. Andersen, F. L., Ouhelli, H. and Kachani, M.), pp. 7284. Brigham Young University Print Services, Provo, Utah, USA.
Schantz, P. M., Chai, J. J., Craig, P. S., Eckert, J., Jenkins, D. J., Macpherson, C. N. L. and Thakur, A. (1995). Epidemiology and control of hydatid disease. In Echinococcus and Hydatid Disease (ed. Thompson, R. C. A. and Lymbery, A. J.), pp. 233331. Cab International, Wallingford, Oxfordshire, UK.
Schantz, P. M., Wang, H., Qiu, J., Liu, F. J., Saito, E., Emshoff, A., Ito, A., Roberts, J. M. and Delker, C. (2003). Echinococcosis on the Tibetan Plateau: prevalence and risk factors for cystic and alveolar echinococcosis in Tibetan populations in Qinghai Province, China. Parasitology 127, S109S120.
Torgerson, P. R. (2003). The use of mathematical models to simulate control options for echinococcosis. Acta Tropica 85, 211221.
Torgerson, P. R. (2013). The emergence of echinococcosis in central Asia. Parasitology 140, 16671673.
Torgerson, P. R. and Heath, D. D. (2003). Transmission dynamics and control options for Echinococcus granulosus . Parasitology 127, 143158.
Torgerson, P. R., Karaeva, R. R., Corkeri, N., Abdyjaparov, T. A., Kuttubaev, O. T. and Shaikenov, B. S. (2003). Human cystic echinococcosis in Kyrgyzstan: an epidemiological study. Acta Tropica 85, 5161.
Torgerson, P. R., Oguljahan, B., Muminov, A. E., Karaeva, R. R., Kuttubaev, O. T., Aminjanov, M. and Shaikenov, B. (2006). Present situation of cystic echinococcosis in Central Asia. Parasitology International 55, S207S212.
Usubalieva, J., Minbaeva, G., Ziadinov, I., Deplazes, P. and Torgerson, P. R. (2013). Human alveolar echinococcosis in Kyrgyzstan. Emerging Infectious Diseases 19, 10951097.
Valadez, J. J., Weiss, W., Leburg, C. and Davis, R. (2002). Assessing community health programs; a participant's manual and workbook. Using LQAS for baseline surveys and regular monitoring. http://www.coregroup.org/storage/documents/LQAS/Assessing_Community_Health_Programs_A_Participants_Manual_and_Workbook.pdf
van Kesteren, F., Mastin, A., Mytynova, B., Ziadinov, I., Boufana, B., Torgerson, P. R., Rogan, M. T. and Craig, P. S. (2013). Dog ownership, dog behaviour and transmission of Echinococcus spp. in the Alay Valley, southern Kyrgyzstan. Parasitology 140, 16741684.
van Kesteren, F., Qi, X., Tao, J., Feng, X., Mastin, A., Craig, P. S., Vuitton, D. A., Duan, X., Chu, X., Zhu, J. and Hao, W. (2015). Independent evaluation of a canine echinococcosis control programme in Hobukesar County, Xinjiang, China. Acta Tropica 145, 17.
WHO (2010). The Control of Neglected Zoonotic Diseases. Report of the third conference organized with ICONZ, DFID-RIU, Gates Foundation, SOS, EU, TDR and FAO with the participation of ILRI and OIE. A. Shaw. World Health Organization headquarters, Geneva, Switzerland.
WHO (2011). Report of the WHO Informal Working Group on cystic and alveolar echinococcosis surveillance, prevention and control, with the participation of the Food and Agriculture Organization of the United Nations and the World Organisation for Animal Health. WHO/HTM/NTD/NZD/2011·2. Department of Control of Neglected Tropical Diseases, WHO, Geneva, Switzerland.
WHO/OIE (2001). WHO/OIE Manual on Echinococcosis in Humans and Animals: a Public Health Problem of Global Concern. ed. Eckert, J., Gemmell, M. A., Meslin, F. X. and Pawłowski, Z. S. World Health Organization/World Organisation for Animal Health, Paris, France.
World Bank (2010). Kyrgyz Republic EU special facility support to animal health and feeding. Report No.: AB5562. http://www-wds.worldbank.org/external/default/WDSContentServer/WDSP/IB/2010/03/19/000262044_20100319154024/Rendered/PDF/Project0Inform1ment1Appraisal0Stage.pdf

Keywords

Type Description Title
WORD
Supplementary materials

van Kesteren supplementary material
van Kesteren supplementary material 1

 Word (14 KB)
14 KB

Evaluation of the impact of 2 years of a dosing intervention on canine echinococcosis in the Alay Valley, Kyrgyzstan

  • F. VAN KESTEREN (a1) (a2), A. MASTIN (a1), P. R. TORGERSON (a3), BERMET MYTYNOVA (a4) and P. S. CRAIG (a1)...

Metrics

Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed