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Detection of human taeniases in Tibetan endemic areas, China

  • TIAOYING LI (a1), XINGWANG CHEN (a1), TETSUYA YANAGIDA (a2), HAO WANG (a1), CHANGPING LONG (a3), YASUHITO SAKO (a2), MUNEHIR OKAMOTO (a4), YUNFEI WU (a5), PATRICK GIRAUDOUX (a6) (a7), FRANCIS RAOUL (a6), AGATHE NKOUAWA (a2), MINORU NAKAO (a2), PHILIP S. CRAIG (a8) and AKIRA ITO (a2)...

Summary

Detection of taeniasis carriers of Taenia solium is essential for control of cysticercosis in humans and pigs. In the current study, we assessed the positive detection rate of a self-detection tool, stool microscopy with direct smear and coproPCR for taeniasis carriers in endemic Tibetan areas of northwest Sichuan. The self-detection tool through questioning about a history of proglottid expulsion within the previous one year showed an overall positive detection rate of more than 80% for Taenia saginata, T. solium and T. asiatica. The positive detection rate was similar for T. saginata and T. solium. In 132 taeniid tapeworm carriers, 68 (51·5%) were detected by microscopy and 92 (69·7%) were diagnosed by coproPCR. A combination of microscopy and coproPCR increased the positive detection rate to 77·3%. There remained 10 cases (7·6%) coproPCR negative but microscopy positive. Due to the high cost and complicated process, coproPCR is required for the identification of Taenia species only when necessary, though it had a significant higher positive detection rate than microscopy. Combined use of self-detection and stool microscopy are recommended in community-based mass screening for taeniases in this Tibetan area or in other situation-similar endemic regions.

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Corresponding author

*Corresponding author: Institute of Parasitic Diseases, Sichuan Centers for Disease Control and Prevention, 6 Zhong Xue Road, Chengdu 610041, Sichuan Province, China. Tel: + 86 28 85589532. Fax: +86 28 85589563. E-mail: litiaoying@sina.com

References

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