Skip to main content Accessibility help
×
Home

Naturalistic Action Performance Distinguishes Amnestic Mild Cognitive Impairment from Healthy Aging

  • David A. Gold (a1), Norman W. Park (a1), Kelly J. Murphy (a2) (a3) and Angela K. Troyer (a2) (a3)

Abstract

Individuals with amnestic mild cognitive impairment (aMCI) show minor decrements in their instrumental activities of daily living (IADL). Sensitive measures of IADL performance are needed to capture the mild difficulties observed in aMCI groups. Routine naturalistic actions (NAs) are familiar IADL-type activities that require individuals to enact everyday tasks such as preparing coffee. In the current study we examined the extent to which NAs could be used to help facilitate differential diagnosis of aMCI relative to composite measures of episodic memory, semantic knowledge, and executive function. Healthy older adults (n=24) and individuals with aMCI (n=24) enacted two highly familiar NAs and completed tests of episodic memory, semantic knowledge, and executive function. Binary logistic regression was used to predict group membership (aMCI vs. control participants). The regression analyses indicated that NA performance could reliably predict group membership, over and above measures of cognitive functioning. These findings indicated that NA performance can be used to help facilitate differential diagnosis of healthy aging and aMCI and used as an outcome measure in intervention studies. (JINS, 2015, 21, 419–428)

Copyright

Corresponding author

Correspondence and reprint requests to: David Gold, Krembil Neuroscience Centre, University Health Network, Toronto Western Hospital, Neuropsychology Clinic, 4F-409, 399 Bathurst St., Toronto, Ontario M5T 2S8. E-mail: david.gold@uhn.ca

References

Hide All
Albert, M.S., DeKosky, S.T., Dickson, D., Dubois, B., Feldman, H.H., Fox, N.C., & Phelps, C.H. (2011). The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimer’s and Dementia, 7(3), 270279 http://doi.org/10.1016/j.jalz.2011.03.008
Almeida, Q.J., Black, S.E., & Roy, E.A. (2002). Screening for apraxia: A short assessment for stroke patients. Brain and Cognition, 48(2-3), 253258 http://doi.org/10.1006/brcg.2001.1356
Bailey, H.R., Kurby, C.A., Giovannetti, T., & Zacks, J.M. (2013). Action perception predicts action performance. Neuropsychologia, 51(11), 22942304 http://doi.org/10.1016/j.neuropsychologia.2013.06.022
Bangen, K.J., Jak, A.J., Schiehser, D.M., Delano-Wood, L., Tuminello, E., Han, S.D., & Bondi, M.W. (2010). Complex activities of daily living vary by mild cognitive impairment subtype. Journal of the International Neuropsychological Society, 16(4), 630639 http://doi.org/10.1017/S1355617710000330
Belleville, S. (2008). Cognitive training for persons with mild cognitive impairment. International Psychogeriatrics, 20, 5766
Brandt, J., & Benedict, R.H.B. (2001). Hopkins Verbal Learning Test–Revised: Professional manual. Lutz, FL: Psychological Assessment Resources.
Brown, P.J., Devanand, D.P., Liu, X., & Caccappolo, E. (2011). Functional impairment in elderly patients with mild cognitive impairment and mild Alzheimer disease. Archives of General Psychiatry, 68(6), 617.
Burton, C.L., Strauss, E., Bunce, D., Hunter, M.A., & Hultsch, D.F. (2009). Functional abilities in older adults with mild cognitive impairment. Gerontology, 55(5), 570581 http://doi.org/10.1159/000228918
Buxbaum, L.J., & Saffran, E.M. (2002). Knowledge of object manipulation and object function: Dissociations in apraxic and nonapraxic subjects. Brain and Language, 82(2), 179199 http://doi.org/10.1016/S0093-934X(02)00014-7
Bylsma, F.W., Carison, M.C., Schretlen, D., Zonderman, A., & Resnick, S. (1997). Rey-Osterrieth Complex Figure Test (CFT). Q-Score performance in 328 healthy adults aged 20 to 94. Journal of the International Neuropsychological Society, 3, 70.
Delis, D.C., Kaplan, E., & Kramer, J.H. (2001). Delis-Kaplan Executive Function System (D-KEFS): Examiner’s manual. San Antonio, TX: Psychological Corporation.
Farias, S.T., Mungas, D., Harvey, D.J., Simmons, A., Reed, B.R., & DeCarli, C. (2011). The Measurement of Everyday Cognition (ECog): Development and validation of a short form. Alzheimer’s & Dementia, 7(6), 593601 http://doi.org/10.1016/j.jalz.2011.02.007
Farias, S.T., Mungas, D., Reed, B.R., Harvey, D., Cahn-Weiner, D., & DeCarli, C. (2006). MCI is associated with deficits in everyday functioning. Alzheimer Disease and Associated Disorders, 20(4), 217.
Fastenau, P.S., Denburg, N.L., & Hufford, B.J. (1999). Adult norms for the Rey-Osterrieth complex figure test and for supplemental recognition and matching trials from the extended complex figure test. The Clinical Neuropsychologist, 13(1), 3047 http://doi.org/10.1076/clin.13.1.30.1976
Folstein, M.F., Folstein, S.E., & McHugh, P.R. (1975). “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12(3), 189198
Giovannetti, T., Bettcher, B.M., Brennan, L., Libon, D.J., Burke, M., Duey, K., & Wambach, D. (2008). Characterization of everyday functioning in mild cognitive impairment: A direct assessment approach. Dementia and Geriatric Cognitive Disorders, 25(4), 359365 http://doi.org/10.1159/000121005
Goldberg, T.E., Koppel, J., Keehlisen, L., Christen, E., Dreses-Werringloer, U., Conejero-Goldberg, C., & Davies, P. (2010). Performance-based measures of everyday function in mild cognitive impairment. American Journal of Psychiatry, 167(7), 845853 http://doi.org/10.1176/appi.ajp.2010.09050692
Gold, D.A. (2012). An examination of instrumental activities of daily living assessment in older adults and mild cognitive impairment. Journal of Clinical and Experimental Neuropsychology, 34(1), 1134 http://doi.org/10.1080/13803395.2011.614598
Gold, D.A., Park, N.W., Troyer, A.K., & Murphy, K.J. (2015). Compromised naturalistic action performance in amnestic mild cognitive impairment. Neuropsychology, 29(2), 320333 http://doi.org/10.1037/neu0000132
Griffith, H.R., Belue, K., Sicola, A., Krzywanski, S., Zamrini, E., Harrell, L., & Marson, D.C. (2003). Impaired financial abilities in mild cognitive impairment A direct assessment approach. Neurology, 60(3), 449457 http://doi.org/10.1212/WNL.60.3.449
Ivnik, R.J., Malec, J.F., Smith, G.E., Tangalos, E.G., & Petersen, R.C. (1996). Neuropsychological tests’ norms above age 55: COWAT, BNT, MAE token, WRAT-R reading, AMNART, Stroop, TMT, and JLO. The Clinical Neuropsychologist, 10(3), 262278 http://doi.org/10.1080/13854049608406689
Ivnik, R.J., Malec, J.F., Smith, G.E., Tangalos, E.G., Petersen, R.C., Kokmen, E., & Kurland, L.T. (1992). Mayo’s older Americans normative studies: WMS-R norms for ages 56 to 94. Clinical Neuropsychologist, 6(Suppl. 1), 4982 http://doi.org/10.1080/13854049208401879
Jefferson, A.L., Byerly, L.K., Vanderhill, S., Lambe, S., Wong, S., Ozonoff, A., & Karlawish, J.H. (2008). Characterization of activities of daily living in individuals with mild cognitive impairment. The American Journal of Geriatric Psychiatry, 16(5), 375383 http://doi.org/10.1097/JGP.0b013e318162f197
Jekel, K., Damian, M., Wattmo, C., Hausner, L., Bullock, R., Connelly, P.J., & Frölich, L. (2015). Mild cognitive impairment and deficits in instrumental activities of daily living: A systematic review. Alzheimer’s Research & Therapy, 7(1), 17 http://doi.org/10.1186/s13195-015-0099-0
Kaplan, E., Goodglass, H., & Weintraub, S. (1983). Boston Naming Test. Philadelphia, PA: Lea & Febiger.
Lawton, M.P., & Brody, E.M. (1969). Assessment of older people: Self-maintaining and instrumental activities of daily living. The Gerontologist, 9(3), 179186
Loeb, P.A. (1996). ILS: Independent Living Scales manual. San Antonio, TX: Psychological Corporation.
Loewenstein, D.A., Amigo, E., Duara, R., Guterman, A., Hurwitz, D., Berkowitz, N., & Gittelman, B. (1989). A new scale for the assessment of functional status in Alzheimer’s disease and related disorders. Journal of Gerontology, 44(4), P114P121
Meusel, L.A.C., Kansal, N., Tchistiakova, E., Yuen, W., MacIntosh, B.J., Greenwood, C.E., & Anderson, N.D. (2014). A systematic review of type 2 diabetes mellitus and hypertension in imaging studies of cognitive aging: Time to establish new norms. Frontiers in Aging Neuroscience, 6, 148 http://doi.org/10.3389/fnagi.2014.00148
Meyers, L.S., Gamst, G., & Guarino, A.J. (2013). Applied multivariate research: Design and interpretation (2nd ed.). Thousand Oaks, CA: SAGE Publications.
Okonkwo, O.C., Wadley, V.G., Griffith, H.R., Ball, K., & Marson, D.C. (2006). Cognitive correlates of financial abilities in mild cognitive impairment. Journal of the American Geriatrics Society, 54(11), 17451750 http://doi.org/10.1111/j.1532-5415.2006.00916.x
Park, N.W., Lombardi, S., Gold, D.A., Tarita-Nistor, L., Gravely, M., Roy, E.A., & Black, S.E. (2012). Effects of familiarity and cognitive function on naturalistic action performance. Neuropsychology, 26(2), 224237 http://doi.org/10.1037/a0026324
Pereira, F.S., Yassuda, M.S., Oliveira, A.M., Diniz, B.S., Radanovic, M., Talib, L.L., & Forlenza, O.V. (2010). Profiles of functional deficits in mild cognitive impairment and dementia: Benefits from objective measurement. Journal of the International Neuropsychological Society, 16(02), 297305 http://doi.org/10.1017/S1355617709991330
Peres, K., Helmer, C., Amieva, H., Orgogozo, J.M., Rouch, I., Dartigues, J.F., & Barberger-Gateau, P. (2008). Natural history of decline in instrumental activities of daily living performance over the 10 years preceding the clinical diagnosis of dementia: A prospective population-based study. Journal of the American Geriatrics Society, 56(1), 3744 http://doi.org/10.1111/j.1532-5415.2007.01499.x
Perneczky, R., Pohl, C., Sorg, C., Hartmann, J., Tosic, N., Grimmer, T., & Kurz, A. (2006). Impairment of activities of daily living requiring memory or complex reasoning as part of the MCI syndrome. International Journal of Geriatric Psychiatry, 21(2), 158162 http://doi.org/10.1002/gps.1444
Petersen, R.C. (2004). Mild cognitive impairment as a diagnostic entity. Journal of Internal Medicine, 256(3), 183194 http://doi.org/10.1111/j.1365-2796.2004.01388.x
Puente, A.N., Terry, D.P., Faraco, C.C., Brown, C.L., & Miller, L.S. (2014). Functional impairment in mild cognitive impairment evidenced using performance-based measurement. Journal of Geriatric Psychiatry and Neurology, 27, 253258. 0891988714532016. http://doi.org/10.1177/0891988714532016
Purser, J.L., Fillenbaum, G.G., Pieper, C.F., & Wallace, R.B. (2005). Mild cognitive impairment and 10-year trajectories of disability in the Iowa established populations for epidemiologic studies of the elderly cohort. Journal of the American Geriatrics Society, 53(11), 19661972 http://doi.org/10.1111/j.1532-5415.2005.53566.x
Reppermund, S., Brodaty, H., Crawford, J.D., Kochan, N.A., Draper, B., Slavin, M.J., & Sachdev, P.S. (2013). Impairment in instrumental activities of daily living with high cognitive demand is an early marker of mild cognitive impairment: The Sydney memory and ageing study. Psychological Medicine, 43(11), 24372445 http://doi.org/10.1017/S003329171200308X
Reppermund, S., Sachdev, P.S., Crawford, J., Kochan, N.A., Slavin, M.J., Kang, K., & Brodaty, H. (2011). The relationship of neuropsychological function to instrumental activities of daily living in mild cognitive impairment. International Journal of Geriatric Psychiatry, 26(8), 843852 http://doi.org/10.1002/gps.2612
Rueda, A.D., Lau, K.M., Saito, N., Harvey, D., Risacher, S.L.,Aisen, P.S., Alzheimer’s Disease Neuroimaging Initiative (2014). Self-rated and informant-rated everyday function in comparison to objective markers of Alzheimer’s disease. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association http://doi.org/10.1016/j.jalz.2014.09.002
Schmitter–Edgecombe, M., McAlister, C., & Weakley, A. (2012). Naturalistic assessment of everyday functioning in individuals with mild cognitive impairment: The day-out task. Neuropsychology, 26(5), 631 http://doi.org/10.1037/a0029352
Schwartz, M.F., Reed, E.S., Montgomery, M., Palmer, C., & Mayer, N.H. (1991). The quantitative description of action disorganisation brain damage: A case study. Cognitive Neuropsychology, 8(5), 381414.
Schwartz, M.F., Segal, M., Veramonti, T., Ferraro, M., & Buxbaum, L.J. (2002). The Naturalistic Action Test: A standardised assessment for everyday action impairment. Neuropsychological Rehabilitation, 12(4), 311339 http://doi.org/10.1080/09602010244000084
Sikkes, S.A., de Lange-de Klerk, E.S., Pijnenburg, Y.A., Scheltens, P., & Uitdehaag, B.M. (2009). A systematic review of Instrumental Activities of Daily Living scales in dementia: Room for improvement. Journal of Neurology, Neurosurgery, and Psychiatry, 80(1), 712 http://doi.org/10.1136/jnnp.2008.155838
Spreen, O., & Strauss, E. (1998). A compendium of neuropsychological tests: Administration, norms, and commentary (2nd ed.). New York: Oxford University Press.
Troyer, A.K., D’Souza, N.A., Vandermorris, S., & Murphy, K.J. (2011). Age-related differences in associative memory depend on the types of associations that are formed. Aging, Neuropsychology, and Cognition, 18(3), 340352 http://doi.org/10.1080/13825585.2011.553273
Troyer, A.K., Murphy, K.J., Anderson, N.D., Hayman-Abello, B.A., Craik, F.I.M., & Moscovitch, M. (2008). Item and associative memory in amnestic mild cognitive impairment: Performance on standardized memory tests. Neuropsychology, 22(1), 1016 http://doi.org/10.1037/0894-4105.22.1.10
Tuokko, H., Morris, C., & Ebert, P. (2005). Mild cognitive impairment and everyday functioning in older adults. Neurocase, 11(1), 4047 http://doi.org/10.1080/13554790490896802
Wadley, V.G., Okonkwo, O., Crowe, M., Vance, D.E., Elgin, J.M., Ball, K.K., & Owsley, C. (2009). Mild cognitive impairment and everyday function: An investigation of driving performance. Journal of Geriatric Psychiatry and Neurology, 22(2), 8794 http://doi.org/10.1177/0891988708328215
Warrington, E.K., & James, M. (1991). The Visual Object and Space Perception Battery. Bury St Edmunds, UK: Thames Valley Test Company.
Wechsler, D. (1987). The Wechsler Memory Scale—Revised. San Antonio, TX: Psychological Corporation.
Wechsler, D. (1997). The Wechsler Adult Intelligence Scale-III. San Antonio, TX: Psychological Corporation.
Willis, S., Jay, G., Diehl, M., & Marsiske, M. (1992). Longitudinal change and prediction of everyday task competence in the elderly. Research on Aging, 14(1), 6891 http://doi.org/10.1177/0164027592141004
Zigmond, A.S., & Snaith, R.P. (1983). The Hospital Anxiety and Depression Scale. Acta Psychiatrica Scandinavica, 67(6), 361370 http://doi.org/10.1111/j.1600-0447.1983.tb09716.x

Keywords

Metrics

Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed