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Performance on the CERAD neuropsychology battery of two samples of Japanese-American elders: Norms for persons with and without dementia

Published online by Cambridge University Press:  11 April 2005

Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, North Carolina Geriatric Research, Education, and Clinical Center, VA Medical Center, Durham, North Carolina
Department of Psychosocial and Community Health, University of Washington, Seattle, Washington
Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, North Carolina
Department of Medicine, University of Hawaii, John A. Burns School of Medicine, Honolulu, Hawaii
Department of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, Florida
Center for Mental Health Services, Substance Abuse and Mental Health Services Administration, Department of Health and Human Services, Rockville, Maryland
Division of Neurology, Department of Medicine, Duke University Medical Center, Durham, North Carolina
Center for Health Studies, Group Health Cooperative and University of Washington, Seattle, Washington Departments of Medicine and Health Services, University of Washington, Seattle, Washington
Department of Medicine, University of Hawaii, John A. Burns School of Medicine, Honolulu, Hawaii


Norms for cognitive measures used to assess dementia are scant for minority groups, in particular for older Japanese Americans. Using the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) Neuropsychology Battery, we compared the baseline performance of demented and nondemented Japanese Americans. Participants came from two harmonized epidemiological studies of dementia which were examined separately: the Kame Project, Seattle (350 men and women; 201 nondemented), age 65 and older; Honolulu-Asia Aging Study (HAAS), Hawaii (418 men; 120 nondemented), age 71 and older. The measures examined were Verbal Fluency; abbreviated Boston Naming; constructional praxis; and Word List Learning, Recall, and Recognition. Within each study, the CERAD measures distinguished between nondemented participants and those with mild cognitive impairment. Among persons with dementia, average level of performance decreased as severity of dementia increased. Determinants of score (age, education, language of administration, stage of dementia) varied between the two studies. Among Japanese Americans, the CERAD Neuropsychology Battery distinguished nondemented persons from those with dementia, but was less consistent in distinguishing levels of severity of dementia. This battery is useful for comparative epidemiological studies of dementia in minority populations. (JINS, 2005, 11, 192–201.)

Research Article
© 2005 The International Neuropsychological Society

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