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P-190 - the Factors Associated With Occurrence of Suicidal Risk After Treatment of Ssri in Bipolar Disorder With Their First Depressive Episode

Published online by Cambridge University Press:  15 April 2020

Z. Li ,
C. Yuan ,
Z. Wu ,
W. Hong  and
Y. Fang
Z. Li
Affiliation:
Department of Mood Disorder, Shanghai Mental Health Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China
C. Yuan
Affiliation:
Department of Mood Disorder, Shanghai Mental Health Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China
Z. Wu
Affiliation:
Department of Mood Disorder, Shanghai Mental Health Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China
W. Hong
Affiliation:
Department of Mood Disorder, Shanghai Mental Health Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China
Y. Fang
Affiliation:
Department of Mood Disorder, Shanghai Mental Health Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China

Abstract

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Objective:

To explore the factors associated with occurrence of suicidal risk after treatment of SSRI in bipolar disorder with their first depressive episode.

Methods:

One hundred and seventy seven bipolar patients were enrolled in this retrospective study. One hundred fifty four patients were included in non-occurrence of suicidal risk group, while twenty three were included in occurrence of suicidal risk group. To compare the demographic and clinic features between these two groups. Stepwise Logistic regression model was used to identify the associated factors. Concordance statistics (i.e. the area under the ROC curve) was used to compute the discrimination of the associated factors, and Hosmer-Lemeshow goodness-of-fit statistic was used to measure the goodness-of-fit.

Results:

Clinical features associated with occurrence of suicidal risk after treatment of SSRI in bipolar disorder were as follows: psychotic symptom and symptom of irritability. The odd ratio was 6.23 and 4.04 separately.

Conclusion:

This study demonstrated indicated that psychotic symptom and symptom of irritability were associated with occurrence of suicidal risk after treatment of SSRI in bipolar disorder, and it suggested that these two symptoms might be potential to be the predictors of occurrence of suicidal risk after treatment of SSRI in bipolar disorder.

Type
Abstract
Information
European Psychiatry , Volume 27 , Issue S1: Abstracts of the 20th European Congress of Psychiatry , 2012 , pp. 1
Copyright
Copyright © European Psychiatric Association 2012
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