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P-1220 - Cognitive Reserve Predicts Insight in Psychosis When Cannabis use Moderate This Relation: a Longitudinal Study one Year Follow-up

Published online by Cambridge University Press:  15 April 2020

J. Cartón Costa ,
A. García Guerrero ,
J.I. Eguíluz Uruchurtu ,
I. Querejeta Ayerdi ,
E. Bengoetxea Noreña ,
A. Zabala Rabadán ,
M. Fernández Hernández ,
K. Haidar  and
M. Gutiérrez Fraile
J. Cartón Costa
Affiliation:
Department of Psychiatry, Osakidetza, Donosti Hospital, San Sebastian
A. García Guerrero
Affiliation:
Faculty of Psychology and Education, University of Deusto, Bilbao
J.I. Eguíluz Uruchurtu
Affiliation:
Faculty of Psychology and Education, University of Deusto, Bilbao Department of Psychiatry, Osakidetza, Cruces Hospital, Barakaldo
I. Querejeta Ayerdi
Affiliation:
Department of Psychiatry, Osakidetza, Donosti Hospital, San Sebastian Faculty of Psychology and Education, University of Deusto, Bilbao
E. Bengoetxea Noreña
Affiliation:
Faculty of Psychology and Education, University of Deusto, Bilbao
A. Zabala Rabadán
Affiliation:
Faculty of Psychology and Education, University of Deusto, Bilbao CIBERSAM, Bilbao
M. Fernández Hernández
Affiliation:
Basque Country University, Leioa
K. Haidar
Affiliation:
Basque Country University, Leioa
M. Gutiérrez Fraile
Affiliation:
Faculty of Psychology and Education, University of Deusto, Bilbao Basque Country University, Leioa Department of Psychiatry, Osakidetza, Santiago Apostol Hospital, Vitoria, Spain

Abstract

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Introduction

Poor insight is a distinctive feature of the psychotic spectrum disorders. One of the theories of the etiology of awareness is the neuropsychological view which suggests that there is an association of awareness, cognition and brain changes in psychosis. But the relationship of cognitive reserve, insight and drug use is still an unexplored field in the psychosis literature.

The aim of this research is to analyze the possible moderator effect of cannabis use in the relation between cognitive reserve and insight in psychosis.

Method

A longitudinal study was held with 65 patients with FEP from 3 main hospitals in the Basque Country (Spain). All patients underwent clinical and functional evaluations at base line and longitudinally at one year follow up. Insight was measured using the insight and judgement item (G12) from the Positive and Negative Syndrome Scale (PANSS). The cognitive reserve was measured using the Vocabulary sub-scale from WAIS-III and educational level. Drug use was assessed during the clinical interview.

Results

One year follow-up data were available for 35 patients. Significant relation between the cognitive reserve and G12 item (β = −9.58; p < .05) was found as long as the cannabis use is included as a moderator (β = −9.34; p < .05).

Conclusion

As it is a complex multidimensional concept, a more complete explanatory model of the insight recognizing the functions of the cognitive reserve and others covariates as drug use, defines the role of each variable of the illness and facilitates the objects of treatment definitions.

Funding

Basque Government(2008111010), EITB-Maratoia(BIO 09/EM/015).

Type
Abstract
Information
European Psychiatry , Volume 27 , Issue S1: Abstracts of the 20th European Congress of Psychiatry , 2012 , pp. 1
Copyright
Copyright © European Psychiatric Association 2012
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