Hostname: page-component-7bb8b95d7b-dvmhs Total loading time: 0 Render date: 2024-09-18T02:01:47.957Z Has data issue: false hasContentIssue false
  • English
  • Français

Increased risk of mortality after an acute coronary syndrome among patients with comorbid anxiety and depression

Published online by Cambridge University Press:  16 April 2020

B.D. Thombs ,
R.C. Ziegelstein ,
D.E. Stewart ,
S.E. Abbey  and
S.L. Grace
B.D. Thombs
Affiliation:
Department of Psychiatry, Sir Mortimer B. Davis - Jewish General Hospital and McGill University, Montreal, QC, Canada
R.C. Ziegelstein
Affiliation:
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
D.E. Stewart
Affiliation:
Women's Health Program, University Health Network, Toronto, ON, Canada Faculty of Medicine, University of Toronto, Toronto, ON, Canada
S.E. Abbey
Affiliation:
Women's Health Program, University Health Network, Toronto, ON, Canada Faculty of Medicine, University of Toronto, Toronto, ON, Canada
S.L. Grace
Affiliation:
Women's Health Program, University Health Network, Toronto, ON, Canada Faculty of Medicine, University of Toronto, Toronto, ON, Canada School of Kinesiology and Health Science, York University, Toronto, ON, Canada

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Background and aims:

Symptoms of at least mild depression (Beck Depression Inventory [BDI] >/= 10), are associated with mortality in acute coronary syndrome (ACS) patients. The BDI, however, is largely a measure of general distress and does not discriminate well between anxiety and depression. We examined the independent contributions of anxiety and depression, as classified by the self-report version of the PRIME-MD, to mortality 1-year post-ACS.

Methods:

Prospective observational study of 765 ACS patients assessed with the PRIME-MD and BDI during hospitalization and followed for 1 year. Logistic regression to predict 1-year mortality based on in-hospital assessments.

Results:

Based on the PRIME-MD in-hospital, 99 patients (12.9%) screened positive for panic disorder, 58 (7.6%) for general anxiety disorder, and 174 (22.7%) for depression. Of 266 patients (34.8%) with a BDI >/= 10, 100 (37.6%) had no PRIME-MD diagnosis, 70 (26.3%) had only depression, 23 (8.6%) had only an anxiety disorder, and 73 (27.4%) had depression and an anxiety disorder. Controlling for age, gender, Killip class, prior myocardial infarction (MI), and cardiac diagnosis (MI vs. unstable angina) and compared to patients with no PRIME-MD diagnosis, the odds ratio of mortality was 1.75 (95% confidence interval [CI] 0.66 to 4.64, p = .26) for patients with depression alone, 2.97 (CI 0.93 to 9.55, p = .07) for patients with anxiety alone, and 4.43 (CI 1.72 to 11.40, p < .01) for patients with both depression and anxiety.

Conclusions:

When assessing the psychosocial status of ACS patients, both depression and anxiety should be considered.

Type
Poster Session 2: Anxiety, Stress Related, Impulse and Somatoform Disorders
Information
European Psychiatry , Volume 22 , Issue S1: 15th AEP Congress - Abstract book - 15th AEP Congress , March 2007 , pp. S290
Copyright
Copyright © European Psychiatric Association 2007
Submit a response

Comments

No Comments have been published for this article.