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Fringe phenotypes in autism: a review of clinical, biochemical and cognitive studies

  • Véronique Goussé (a1) (a2), Marie-Hélène Plumet (a1), Nadia Chabane (a1) (a2), Marie-Christine Mouren-Siméoni (a1), Nathalie Ferradian (a3) and Marion Leboyer (a1) (a2) (a3)...

Summary

Progress in identifying the genetic vulnerability factors in autism requires correct identification of the inherited phenotype(s). This can be achieved not only by the accurate description of the affected subject but also by the identification of vulnerability traits in non-affected relatives of autistic probands. This review will focus on this last strategy and principally on clinical, biochemical and cognitive traits.

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*Corresponding author. Tel.: +33-1-49-81-30-51; fax +33-1-49-81-39-51. E-mail address: leboyer@im3.inserm.fr (M. Leboyer).

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Fringe phenotypes in autism: a review of clinical, biochemical and cognitive studies

  • Véronique Goussé (a1) (a2), Marie-Hélène Plumet (a1), Nadia Chabane (a1) (a2), Marie-Christine Mouren-Siméoni (a1), Nathalie Ferradian (a3) and Marion Leboyer (a1) (a2) (a3)...

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Fringe phenotypes in autism: a review of clinical, biochemical and cognitive studies

  • Véronique Goussé (a1) (a2), Marie-Hélène Plumet (a1), Nadia Chabane (a1) (a2), Marie-Christine Mouren-Siméoni (a1), Nathalie Ferradian (a3) and Marion Leboyer (a1) (a2) (a3)...
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