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Failure of fixed-dose verapamil treatment in adult sleep-related enuresis

Published online by Cambridge University Press:  16 April 2020

A Grinshpoon
Affiliation:
Mental Health Center, Israel Defense Forces, Israel
M Mark
Affiliation:
Mental Health Center, Israel Defense Forces, Israel
A Apter
Affiliation:
Geha Psychiatric Hospital, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv
I Modai
Affiliation:
Geha Psychiatric Hospital, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv
A Bleich
Affiliation:
Mental Health Center, Israel Defense Forces, Israel
M Rehavi
Affiliation:
Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv
A Weizman*
Affiliation:
Geha Psychiatric Hospital, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv Felsenstein Medical Research Center, and Geha Psychiatric Hospital, Beilinson Campus, Petah Tiqva, Israel
*
*Correspondence and reprints.
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Summary

Calcium channel blockers increase the capacity of the urinary bladder. The antienuretic activity of verapamil was examined in young adult enuretics. Eleven drug-free, healthy, sleep-related enuretic males, were treated for two weeks with verapamil (240 mg, per os, at 9 pm). Verapamil failed to display an antienuretic effect.

Type
Rapid communication
Copyright
Copyright © European Psychiatric Association 1994

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