Hostname: page-component-848d4c4894-pjpqr Total loading time: 0 Render date: 2024-06-22T00:51:19.541Z Has data issue: false hasContentIssue false
  • English
  • Français

Can cannabis trigger recurrent panic attacks in susceptible patients?

Published online by Cambridge University Press:  16 April 2020

G Langs ,
H Fabisch ,
K Fabisch  and
HG Zapotoczky
G Langs
Affiliation:
Univ Klinik für Psychiatrie, Auenbruggerplatz 22, 8036Graz, Austria
H Fabisch
Affiliation:
Univ Klinik für Psychiatrie, Auenbruggerplatz 22, 8036Graz, Austria
K Fabisch
Affiliation:
Univ Klinik für Psychiatrie, Auenbruggerplatz 22, 8036Graz, Austria
HG Zapotoczky
Affiliation:
Univ Klinik für Psychiatrie, Auenbruggerplatz 22, 8036Graz, Austria
Get access

Summary

Cannabis has been reported to produce acute psychiatric reactions, among these panic anxiety and derealization, which are self-limited. We report on three patients who experienced an initial panic attack during cannabis intake. Anxiety attacks reoccurred after the cessation of intake. Two of these patients had a current depressive disorder, one of them had a single Grand Mal seizure before the onset. We suggest that cannabis may trigger the emergence of recurrent panic attacks and uncover latent panic disorders in vulnerable persons.

Keywords

cannabispanic attackspanic disorderdepression
Type
Case report
Information
European Psychiatry , Volume 12 , Issue 8 , 1997 , pp. 415 - 419
Copyright
Copyright © Elsevier, Paris 1997

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Adamec, REStark-Adamec, CLimbic kindling and animal behavior-implications for human psychopathology associated with complex partial seizures Bio Psychiat 18 1983 269–293Google Scholar
Adams, IBMartin, RMCannabis: pharmacology and toxicology in animals and humans Addiction 91111996 1585–161410.1111/j.1360-0443.1996.tb02264.xCrossRefGoogle ScholarPubMed
Castle, JDAmes, FRCannabis and the brain Aust-N-Z-J Psychiatry 30 1996 179–18310.3109/00048679609076093CrossRefGoogle ScholarPubMed
Dantendorfer, KAmering, MBaischer, WBerger, PSteinberger, KWindhaber, JKatschnig, KIs there a pathophysiological and therapeutic link between panic disorder and epilepsy? Ada Psychiat Scan 91 1995 430–43210.1111/j.1600-0447.1995.tb09804.xCrossRefGoogle Scholar
Dantendorfer, KWindhaber, JMaierhofer, DJackson seizure and panic disorder relieved by carbamazepine Eur Psychiatry 10 1995 370–37110.1016/0924-9338(96)80338-5CrossRefGoogle ScholarPubMed
Ellenhorn, MJBarceloux, DDMedical Toxicology 1988 Elsevier AmsterdamGoogle Scholar
Goddard, AWCharney, DSToward an integrated neurobiology of panic disorder J Clin Psychiatry 58suppl 21997 4–11Google ScholarPubMed
Goddard, GVMclntyre, DCLeech, CKA permanent change in brain function resulting from daily electrical stimulation Exptl Neurology 25 1969 295–33010.1016/0014-4886(69)90128-9CrossRefGoogle ScholarPubMed
Gorman, JMFyer, MRLiebowitz, MRKlein, DFPharmacologic provocation of panic attacks In: Meltzer, HY eds. Psychopharmacology: A third generation of Progress 1987 Raven Press New York985–998Google Scholar
Gorman, JMLiebowitz, MRFyer, AJStein, JA neuroanatomical hypothesis for panic disorder Am J Psychiatry 146 1989 148–161Google ScholarPubMed
Gouzolis, EBorchardt, DHeimle, LA Case of toxic psychosis induced by “EVE” (3,4-Methylene-dioxyethylam-pheta-mine) Arch Gen Psychiatry 1993 50–75Google Scholar
Guttmacher, LBMurphy, DLInsel, TRPharmacologic models of anxiety Comp Psychiatry 24 1983 312–32610.1016/0010-440X(83)90059-7CrossRefGoogle ScholarPubMed
Halikas, JMarijuana use and psychiatric illness In: Miller, LE ed. Marijuana: effects on human behavior 1974 Academic Press New York265–30210.1016/B978-0-12-497050-2.50016-4CrossRefGoogle Scholar
Hemmeter, UHolsboer-Trachsler, ENeuroendokrinologie und Biochemie bei Angsterkrankungen In: Kasper, SMöller, HJ eds. Angstund Panikerkrankungen 1995 G Fischer Stuttgart, Jena179–201Google Scholar
Hermle, LSpitzer, MBorchardt, DGouzolis, EBeziehungen der Modell-bzw.Drogenpsychosen zu schizophrenen Erkrankungen Fortschr Neurot Psychiat 60 1992 383–39210.1055/s-2007-1000662CrossRefGoogle Scholar
Hollister, LECannabis-1988 Acta Psychiatr Scan 78suppl 3451988 108–11810.1111/j.1600-0447.1988.tb08576.xCrossRefGoogle Scholar
Isbell, HGorodetsky, CWJasinski, DClaussen, USpulak, F vonKorte, FEffects of Δ9 trans-tetrahydrocannabinol in man Psychopharmacologia 11 1967 184–188CrossRefGoogle Scholar
Jaffe, JJPsychoactive substance use disorders In: Kaplan, HISadock, BJ eds. Comprehensive Textbook of Psychiatry vol 1 1989 Williams & Williams Baltimore642–698Google Scholar
Klein, DFDelineation of two drug-responsive anxiety syndromes Psychopharmacologia 5 1964 397–40810.1007/BF02193476CrossRefGoogle ScholarPubMed
McCann, UDRicaurte, GAMDMA (“Ecstasy”) and panic disorder: induction by a single dose Biol Psychiatry 32 1992 950–953CrossRefGoogle ScholarPubMed
Margraf, JSchneider, SAngstanfälle und ihre Behandlung 1989 Springer Verlag Berlin, HeidelbergGoogle Scholar
Meyer, RBehavioral pharmacology of marijuana In: Lipton, MADiMascio, AKillam, KF ed. Psychopharmacology: a generation of progress 1978 Raven Press New York1639–1652Google Scholar
Moran, CDepersonalisation and agoraphobia associated with marijuana use Br J Med Psychol 58 1986 187–19610.1111/j.2044-8341.1986.tb02684.xCrossRefGoogle Scholar
Ohlsson, ALindgren, LEWahlen, AAgurell, SHollister, LEGillespie, HHPlasma Δ9tetrahydrocannabinol concentrations and clinical effects after oral and intravenous administration and smoking Clin Pharmacol Ther 28 1980 409–416CrossRefGoogle Scholar
Onaivi, ESChakrabarti, AChaudhuri, GCannabinoid receptor genes Prog Neurobiol 48 1996 275–30510.1016/0301-0082(95)00044-5CrossRefGoogle ScholarPubMed
Pertwee, RGThe central neuropharmacology of psychotropic cannabinoids Pharmacol Ther 36 1988 189–261CrossRefGoogle ScholarPubMed
Rosenberg, RKindling and panic disorder In: Bolwig, TMTrimble, MR eds. The clinical relevance of kindling 1989 Wiley and Sons New York263–273Google Scholar
Roth, MHarper, MTemporal lobe epilepsy and the phobic-anxiety depersonalisation syndrome, part I and II Compr Psychiatry 3 1962 129CrossRefGoogle Scholar
Roy-Byrne, PPUhde, TExogenous factors in panic disorder: clinical and research implications J Clin Psychiatry 49 1988 56–61Google ScholarPubMed
Salkovskis, PMClark, DMCognitive and physiological processes in the maintenance and treatment of panic attacks In: Hand, IWittchen, HU eds.Panic and Phobias 1986 Springer Berlin, Heidelberg, New York90–103CrossRefGoogle Scholar
Seibyl, JPCrystal, JHCharney, DSMarijuana (cannabis) use is anecdotally said to precipitate anxiety symptoms in patients with panic disorder. Is there any research evidence to support this? Also, can Marijuana use precipitate or expose paranoia in patients with an underlying bipolar disorder? J Clin Psychopharmacol 10 1990 78CrossRefGoogle ScholarPubMed
Sheehan, DVSheehan, KHThe classification of anxiety hysterical states: II.Toward a more heuristic classification J Clin Psychopharmacol 261982 386–39310.1097/00004714-198212000-00005CrossRefGoogle ScholarPubMed
Sieghart, WTransmittersysteme und Rezeptoren in der Neurobiologie der Angst In: Kasper, SMöller, HJ eds. Angstund Panikerkrankungen 1995 G Fischer Verlag Jena, Stuttgart202–220Google Scholar
Spitz, MCPanic disorder in seizure patients: a diagnostic pitfall Epilepsia 3211991 33–3810.1111/j.1528-1157.1991.tb05607.xCrossRefGoogle ScholarPubMed
Strian, FPloog, DAnxiety related to central nervous system dysfunction In: Noyes, RRoth, MBurrows, GD eds. Handbook of anxiety vol 2 1988 Elsevier Amsterdam432–475Google Scholar
Thomas, HPsychiatric symptoms in cannabis users Br J Psvchiatry 163 1993 141–14910.1192/bjp.163.2.141CrossRefGoogle ScholarPubMed
Thomas, HA community survey of adverse effects of cannabis use Drug Alcohol Dep 42 1996 201–207CrossRefGoogle ScholarPubMed
Weilburg, JBBear, DMSachs, GThree patients with concomitant panic attacks and seizure disorder: possible clues to the neurology of anxiety Am J Psychiatry 14481987 1053–1056Google ScholarPubMed
Submit a response

Comments

No Comments have been published for this article.