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1678 – Do Vitamin d Levels In Bipolar And Schizophenia Outpatients Differ? Outcome Of a Dutch Cross-sectional Study

Published online by Cambridge University Press:  15 April 2020

R. Boerman ,
D. Cohen  and
P.F. Schulte
R. Boerman
Affiliation:
Severe Mental Illness, Mental Health Organization North-Holland North, Heiloo, The Netherlands
D. Cohen
Affiliation:
Severe Mental Illness, Mental Health Organization North-Holland North, Heerhugowaard, The Netherlands Clinical Epidemiology, University of Groningen, Groningen, The Netherlands
P.F. Schulte
Affiliation:
Short-Term Treatment, Mental Health Organization North-Holland North, Heerhugowaard, The Netherlands

Abstract

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Introduction

Itzhaky (2012) found significantly lower vitamin D level in patients with schizophrenia than in healthy controls.

Objective

Measurement of vitamine-D in bipolar and schizophrenia/schizoaffective outpatients.

Aims

Determining the prevalence of vitamin D deficiency in outpatients with bipolar disorder, schizophrenia or schizoaffective disorder in the Netherlands.

Method

Outpatients in the Alkmaar region aged 18w65 years with a bipolar disorder, Schizophrenia/schizoaffective disorder were asked to add vitamin D levels determination to the annual standard blood sample taking.

Results

111 patients, 54 with schizophrenia/schizoaffective disorder and 57 with bipolar disorder, participated. 58 (53%) was male, mean age 47 (SD 9.9) years. 64 (58%) showed vitamin-D insufficiency (< 50 nmol/L), 32 (29%) vitamin-D deficiency (< 30 nmol/L). 7 (6.3%) female patients aged >50 had a serum level between 30–50 nmol/l. No significant differences were found between bipolar disorder and schizophrenia/schizoaffective disorder.

Conclusion

To prevent osteoporosis, vitamin D supplementation is advised with vitamin D-levels below 30nmol/l or below 50 in women >50 years and men >70 years, (Dutch Health Council). Using to this criterion 39 patients (35%) of the study-population needed vitamine-D supplement. If confirmed, addition of vitamine-D levels to the annual somatic screening of patients with bipolar disorder, schizophrenia/schizoaffective disorder is indicated. Limitation: the impact of the season on vitamine-D levels was not corrected for in either population.

Type
Abstract
Information
European Psychiatry , Volume 28 , Issue S1: Abstracts of the 21th European Congress of Psychiatry , 2013 , 28-E955
Copyright
Copyright © European Psychiatric Association 2013

References

Dutch Health Council (Gezondheidsraad). Evaluatie van voedingsnormen voor vitamine D. Den Haag: Gezondheidsraad, 2012.Google Scholar
Itzhaky, D., et al.Low Serum Vitamin d Concentrations In Patients With Schizophrenia. Isr Med Assoc J 2012; 4: 88–92Google Scholar
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