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What Can Our Nose Tell Us About Possible Treatments for Alzheimer’s Disease?

Published online by Cambridge University Press:  02 December 2014

Samuel Weiss
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Abstract

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Type
Editorial
Information
Canadian Journal of Neurological Sciences , Volume 30 , Issue 1 , February 2003 , pp. 3
Copyright
Copyright © The Canadian Journal of Neurological 2003

References

1. Tropepe, V, Craig, CG, Morshead, CM, van der Kooy, D. Transforming growth factor-alpha null and senescent mice show decreased neural progenitor cell proliferation in the forebrain subependyma. J Neurosci 1997;17:7850–7859.Google Scholar
2. Roberts, E. Alzheimer’s disease may begin in the nose and may be caused by aluminosilicates. Neurobiol Aging 1986;7:561–567.Google Scholar
3. Magavi, SS, Leavitt, BR, Macklis, JD. Induction of neurogenesis in the neocortex of adult mice. Nature 2000;405:951–955.Google Scholar
4. Gould, E, Reeves, AJ, Graziano, MS, Gross, CG. Neurogenesis in the neocortex of adult primates. Science 1999;286:548–552.Google Scholar
5. Christen-Zaech, S, Kraftsik, R, Pillevuit, O. Early Olfactory Involvement in Alzheimer’s Disease. Can J Neurol Sci 2003; 30:20–25 Google Scholar
6. Arvidsson, A, Collin, T, Kirik, D, Kokaia, Z, Lindvall, O. Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat Med 2002;8:963–970.Google Scholar
7. Murphy, C, Gilmore, MM, Seery, CS, Salmon, DP, Lasker, BR. Olfactory thresholds are associated with degree of dementia in Alzheimer’s disease. Neurobiol Aging 1990;11:465–469.CrossRefGoogle ScholarPubMed
8. Perl, DP, Good, PF. Uptake of aluminium into central nervous system along nasal-olfactory pathways. Lancet 1987;1:1028.Google Scholar
9. Miklossy, J, Kraftsik, R, Pillevuit, O, et al. Curly fiber and tangle-like inclusions in the ependyma and choroid plexus--a pathogenetic relationship with the cortical Alzheimer-type changes? J Neuropathol Exp Neurol 1998;57:1202–1212.Google Scholar
10. van der Kooy, D, Weiss, S. Why stem cells? Science 2000;287:1439–1441.Google Scholar
11. Kornack, DR, Rakic, P. The generation, migration, and differentiation of olfactory neurons in the adult primate brain. Proc Natl Acad Sci USA 2001;98:4752–4757.Google Scholar
12. Mesholam, RI, Moberg, PJ, Mahr, RN, Doty, RL. Olfaction in neurodegenerative disease: a meta-analysis of olfactory functioning in Alzheimer’s and Parkinson’s diseases. Arch Neurol 1998;55:84–90.Google Scholar