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Visual Loss Secondary to a Giant Aneurysm in a Patient with Tuberous Sclerosis

Published online by Cambridge University Press:  18 September 2015

Mark Guttman ,
S. Mark Tanen  and
Colin D. Lambert
Mark Guttman
Affiliation:
Department of Neurology, St. Michael’s Hospital, Toronto, Ontario
S. Mark Tanen
Affiliation:
Department of Neurology, St. Michael’s Hospital, Toronto, Ontario
Colin D. Lambert*
Affiliation:
Department of Neurology, St. Michael’s Hospital, Toronto, Ontario
*
St. Michael’s Hospital30 Bond Street, Toronto, Ontario, Canada M5B 1W8
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Abstract

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We report a fifty three year old man who presented with progressive visual loss. Investigation disclosed a giant aneurysm with optic nerve compression, which was successfully treated surgically. The patient had typical skin lesions of tuberous sclerosis, but did not suffer from a seizure disorder or mental retardation. In the past he had had an enucleation for glaucoma secondary to a retinal phakoma.

Cerebral aneurysms are discussed in relation to the tuberous sclerosis disease process. After review of the literature, we propose that the aneurysms are secondary to dysplastic change in the vessel walls, this is in keeping with the abnormal tissue proliferations in this disease.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 11 , Issue 4 , November 1984 , pp. 472 - 474
Copyright
Copyright © Canadian Neurological Sciences Federation 1984

References

Beall, S., Delaney, P. (1983) Tuberous sclerosis with intracranial aneurysms. Arch Neurol 40: 826–827.CrossRefGoogle Scholar
Bender, BL., Jinis, EJ. (1982) The pathology of tuberous sclerosis. Path Annual Part 1, (vol 17), 339–383.Google ScholarPubMed
Bourneville, DM. (1880) Contribution a l’étude de l’idiotie sclerose tubéreuse des circonvolutions cerebrales; idiotie et épilepsie hémiplégique. Arch Neurol (Paris) 1: 81–91.Google Scholar
Davidson, S. (1974) Tuberous sclerosis with fusiform aneurysms of both internal carotid arteries maintained by unilateral visual loss and papilledema. Bull Los Ang Neur Soc 39 (3): 128–132.Google Scholar
Gomez, MR. (1979) Other visceral, vascular and osseous lesions. Tuberous Sclerosis, ed. Gomez, M., New York: Raven Press, pp 171–192.Google Scholar
Hilal, SK., Solomon, GE., Gold, AP., Carter, S. (1971) Primary cerebral arterial occlusive disease in children. Radiology 99: 87–93.CrossRefGoogle ScholarPubMed
Herz, PA., Liebskind, A., Rosenthal, A., Schechter, MM. (1975) Cerebral angiographic changes associated with tuberous sclerosis. Radiology 115: 647–649.CrossRefGoogle ScholarPubMed
Larbie, F., Loire, R., Guibaud, B., Weill, B. (1971) Observation clinique et anatomique aux aneurysm de l’aorte au cours de la sclereuse tube-reuse de Bourneville. Arch Fr Pediat 28: 975–984.Google Scholar
Medley, BE., McLeod, RA., Houser, OW. (1976) Tuberous sclerosis. Seminars in Roentgenology, vol xi (1).Google Scholar
Prompitak, A., Maberley, AL., xsShea, M. (1973) An abortive case of tuberous sclerosis without mental deficiency or epilepsy in an adult. Amer Jour of Ophthamology 76 (2): 255–259.CrossRefGoogle ScholarPubMed
von Recklinghausen, F (1862) Ein Herz von einem Neugeborenen welches mehrere Theils nach aussen, Theils nach den Hohlen prominirende Tumoren (Myomen) trug. Verh Ges Geburtsch Monatschr Beburtsk 20: 1–2.Google Scholar
Robbins, TD., Bernstein, J. (1979) Tuberous Sclerosis, ed. Gomez, M.New York: Raven Press pp 171–192.Google Scholar
Snowdon, JA. (1974) Cerebral aneurysm, renal cysts and hanartomas in a case of tuberous sclerosis. Br Jr of Urology 46: 583.CrossRefGoogle Scholar