Hostname: page-component-84b7d79bbc-5lx2p Total loading time: 0 Render date: 2024-07-31T01:46:00.161Z Has data issue: false hasContentIssue false
  • English
  • Français

Recurrent Aseptic Meningitis Secondary to Intracranial Epidermoids

Published online by Cambridge University Press:  18 September 2015

Werner J. Becker ,
Gordon V. Watters ,
Jean-Pierre de Chadarevian  and
Michel Vanasse
Werner J. Becker*
Affiliation:
The Montréal Childrens’ Hospital, Montréal. Hôpital Sainte-Justine, Montréal
Gordon V. Watters
Affiliation:
The Montréal Childrens’ Hospital, Montréal. Hôpital Sainte-Justine, Montréal
Jean-Pierre de Chadarevian
Affiliation:
The Montréal Childrens’ Hospital, Montréal. Hôpital Sainte-Justine, Montréal
Michel Vanasse
Affiliation:
The Montréal Childrens’ Hospital, Montréal. Hôpital Sainte-Justine, Montréal
*
Calgary General Hospital, Room M3–016, 841 Centre Avenue East, Calgary, Alberta T2E 0A1
Rights & Permissions [Opens in a new window]

Abstract:

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Two patients with recurrent aseptic meningitis are reported. Intracranial epidermoid tumors were eventually found in both patients. CSF changes in our first case with an epidermoid tumor were similar to those reported in Mollaret’s meningitis, with an initial polymorphonuclear pleocytosis early in each attack, followed by a lymphocytic predominance several days later. Large cells which proved to be macrophages were also seen in the CSF of this patient. Both patients had meningitis attacks for several years before the underlying epidermoid tumor was found. Mollaret’s meningitis remains a diagnosis of exclusion. These patients should remain tumor suspects for many years and deserve careful and repeated investigation.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 11 , Issue 3 , August 1984 , pp. 387 - 389
Copyright
Copyright © Canadian Neurological Sciences Federation 1984

References

Bernat, JL (1976) Glioblastoma multiforme and the meningeal syndrome. Neurology 26: 1071–1074.CrossRefGoogle ScholarPubMed
Bruyn, GW, Straathof, LJA, Raymakers, GMJ (1962) Mollaret’s meningitis: differential diagnosis and diagnostic pitfalls. Neurology 12: 745–53.CrossRefGoogle ScholarPubMed
Cantu, RC, Wright, RL, (1968) Aseptic meningitic syndrome with cauda equina epidermoid tumor. J Pediatr 73: 114–116.CrossRefGoogle ScholarPubMed
Coleman, WS, Lischner, HW, Grover, WD (1975) Recurrent aseptic meningitis without sequelae. J Pediatr 87: 89–91.CrossRefGoogle ScholarPubMed
de Chadarevian, JP, Becker, WJ (1980) Mollaret’s recurrent aseptic meningitis: relationship to epidermoid cysts. J Neuropathol Exp Neurol 39: 661–669.CrossRefGoogle ScholarPubMed
De Klerk, DJ, Spence, J (1974) Chemical meningitis with intracranial tumors. S Afr Med J 48: 131–135.Google Scholar
Feld, M, Brumpt, L, Chambon, Met al. (1955) Kyste hydatique autochtone parieto-occipital gauche, annoncé par une méningite lymphocytaire à réchutes. Ablation, guerison. Rev Neurol (Paris) 92: 297–300.Google Scholar
Finelle, PF, Yockey, CC, Hebert, AJ (1976) Recurrent aseptic meningitis in an elderly man. JAMA 235: 1142–1143.CrossRefGoogle Scholar
Galdi, AP (1979) Benign recurrent aseptic meningitis (Mollaret’s meningitis). Case report and clinical review. Arch Neurol 36:657–658.CrossRefGoogle ScholarPubMed
Gledhill, RF, Lewis, PD, Marsden, CDet al. (1975) Is Mollaret’s meningitis another periodic disorder responsive to colchicine? Lancet 2: 415.CrossRefGoogle ScholarPubMed
Guran, P, Beal, G, Browaeys, J, et al. (1977) Meningite multirecurrente benigne. Rev Neurol (Paris) 133: 245–254.Google ScholarPubMed
Haynes, BF, Wright, R, McCracken, JP (1976) Mollaret’s meningitis: A report of three cases. JAMA 236: 1967–1969.CrossRefGoogle ScholarPubMed
Hermans, PE, Goldstein, NP, Wellman, WE (1972) Mollaret’s meningitis and differential diagnosis of recurrent meningitis. Am J Med 52: 128–140.CrossRefGoogle ScholarPubMed
Labrisseau, A, Renevey, F, Brochu, P, et al. (1980) Recurrent chemical meningitis due to an intraspinal cystic teratoma. J Neurosurg 52: 715–717.CrossRefGoogle Scholar
Leal, O, Miles, J (1978) Epidermoid cyst in the brainstem. J Neurosurg 48:811–813.CrossRefGoogle Scholar
Mollaret, P (1977) La méningite endothélio (?) – Leucocytaire multirecurrente benigne. Rev Neurol (Paris) 133: 225–242.Google Scholar
Mora, JS, Gimeno, A (1980) Mollaret’s meningitis: report of a case with recovery after colchicine. Ann Neurol 8: 631–633.CrossRefGoogle ScholarPubMed
Nadao, T, Miura, R (1971) Recurrent virus meningitis. Pediatr 47:773–776.Google Scholar
Ross Russell, RW, Pennybacker, JB (1961) Craniopharyngioma in the elderly. J Neurosurg Psychiat 24: 1–13.CrossRefGoogle Scholar
Saint-Martin, M, Duplantis, F, Laverdiere, Met al. (1982) Le Meningite de Mollaret. Can J Neurol Sci 9: 41–43.CrossRefGoogle Scholar
Schotland, DL, Wolf, SM, White, HHet al. (1967) Neurologic aspects of Behcet’s disease. Am J Med 43: 227–253.Google Scholar
Schwartz, JF, Balentine, JD (1978) Recurrent meningitis due to an intracranial epidermoid. Neurology 28: 124–129.CrossRefGoogle Scholar
Stamm, AM, Livingston, WK, Cobbs, CGet al. (1984) Failure of colchicine in the treatment of Mollaret’s meningitis. Arch Intern Med (in press).CrossRefGoogle ScholarPubMed
Steel, JG, Dix, RD, Baringer, JR (1982) Isolation of Herpes simplex virus type 1 in recurrent (Mollaret) meningitis. Ann Neurol 11: 17–21.CrossRefGoogle Scholar
Swithinbank, IM, Rake, MO (1978) A case of Mollaret’s meningitis associated with lymphoma. Postgrad Med J 54: 682–685.CrossRefGoogle ScholarPubMed
Tyler, KL, Adler, D (1983) Twenty-eight years of benign recurring Mollaret meningitis. Arch Neurol 40: 42–43.CrossRefGoogle ScholarPubMed
Welsby, P, Smith, C (1977) Recurrent sterile meningitis as a manifestation of systemic lupus erythematosus. Scand J Infec Dis 9: 149–150.CrossRefGoogle Scholar