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Progress in Clinical Neurosciences: A Forum on the Early Management of Parkinson's Disease

Published online by Cambridge University Press:  02 December 2014

Anthony E. Lang ,
Janis Miyasaki ,
C. Warren Olanow ,
A. Jon Stoessl  and
Oksana Suchowersky
Anthony E. Lang*
Affiliation:
Division of Neurology, Department of Medicine, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada
Janis Miyasaki
Affiliation:
Division of Neurology, Department of Medicine, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada
C. Warren Olanow
Affiliation:
Department of Neurology, Mount Sinai School of Medicine, Toronto, Ontario, Canada
A. Jon Stoessl
Affiliation:
Pacific Parkinson's Research Center, University of British Columbia, Vancouver, British Columbia, Canada
Oksana Suchowersky
Affiliation:
Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
*
Movement Disorders Center, Toronto Western Hospital, 399 Bathurst St.,7McL, Toronto, ON M5T 2S8 Canada
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Abstract:

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There are numerous concerns related to treatment choices involving early dopaminergic therapy in Parkinson's disease. These include the effect on the underlying progression of the neurodegenerative process as well as the development of motor complications such as fluctuations and dyskinesias. A number of recent basic and clinical studies have provided new insights but have also added confusion and controversy. This report summarizes presentations and discussion dealing with these issues from a one-day symposium involving Canadian Movement Disorders neurologists.

Résumé:

RÉSUMÉ:

Le traitement précoce de la maladie de Parkinson au moyen d’agents dopaminergiques soulève plusieurs questions, entre autres son effet sur la progression du processus neurodégénératif et sur le développement de complications motrices telles les fluctuations et les dyskinésies. Des études fondamentales et cliniques récentes ont fourni de nouvelles avenues de réflexion, mais elles ont également suscité la confusion et la controverse. Cet article résume les présentations et les discussions sur le sujet lors d’un symposium d’une journée tenue par des neurologues intéressés par les troubles du movement (Canadian Movement Disorders Group).

Type
Review Article
Information
Canadian Journal of Neurological Sciences , Volume 32 , Issue 3 , August 2005 , pp. 277 - 286
Copyright
Copyright © The Canadian Journal of Neurological 2005

References

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