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Primary CNS Lymphoma: Lymphomatous Meningitis Presenting as a Cauda Equina Lesion in an AIDS Patient

  • Pavel Klein (a1), Gary Zientek (a2), Scott R. VandenBerg (a2) and Eric Lothman (a1)

Abstract:

Neurologic complications of the acquired immune deficiency syndrome (AIDS) most often present as brain dysfunction and/or a polyneuropathy. We describe a unique neurological problem of a woman with AIDS who presented with a Cauda equina mass due to primary CNS lymphoma. She subsequently developed a fulminant lymphomatous meningitis and died. Although previously rare, primary spinal cord lymphoma is expected to be encountered more often with the current AIDS epidemic and may be difficult to distinguish from infectious mass lesions.

RÉSUMÉ:

Les complications neurologiques du syndrome d'immuno-déficience acquise se présentent le plus souvent comme une dysfonction cérébrale et/ou une polyneuropathie. Nous décrivons un problème neurologique unique chez une femme atteinte du SIDA, qui s'est présentée avec une masse à la queue de cheval due à un lymphome primaire du SNC. Elle a ultérieurement développé une méningite lymphomateuse fulminante et elle est décédée. Même si cette entité était rare dans le passé, il est à prévoir que les lymphomes primaires de la moelle épinière seront plus fréquents à cause de l'épidémie actuelle de SIDA et il peut être difficile de les distinguer des lésions tumorales infectieuses.

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Copyright

Corresponding author

Department of Neurology, Box 394, University of Virginia Medical Center, Charlottesville, Virginia 22908 U.S.A.

References

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