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Graves' Disease and Subarachnoid Hemorrhage: A Possible Familial Association

Published online by Cambridge University Press:  18 September 2015

Richard Leblanc  and
Andrés M. Lozano
Richard Leblanc*
Affiliation:
Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montréal
Andrés M. Lozano
Affiliation:
Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montréal
*
Montreal Neurological Institute, 3801 University Street, Montreal, Quebec, Canada H3A 2B4
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Abstract:

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We report the occurrence of cerebral aneurysms and subarachnoid hemorrhage (SAH) in a family with Graves' disease (GD). Nine affected individuals across three generations have GD alone; three in the same generation have SAH without GD; and three others in the same sibship have both conditions. The familial association of GD and SAH has not been previously described. The occurrence of these disorders in individuals of the same family and their coexistence in the same individuals suggests a possible genetic determination for some cerebral aneurysms and may imply a genetic locus related to that of Graves' disease.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 14 , Issue 4 , November 1987 , pp. 638 - 641
Copyright
Copyright © Canadian Neurological Sciences Federation 1987

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