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Effect of Therapy on Cerebral Blood Flow Following Aneurysm Surgery

  • Bryce Weir (a1), Roberto Deleo (a1) and Devidas Menon (a1)

Summary

The authors report on a patient with a ruptured anterior communicating aneurysm treated surgically on the day following her subarachnoid hemorrhage (SAH). Repeated measurements of cerebral blood flow (rCBF) were carried out using the inhalational Xenon 133 method. Dramatic acute increases in rCBF occurred, coincident with clinical improvement, following mannitol, CSF drainage and dopamine. Later, further elevation to normal levels occurred following ventriculo-peritoneal shunting.

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Copyright

Corresponding author

Neurosurgical Associates, Suite 520 – 8409 112th Avenue, Edmonton, Alberta, T6G 1K6, Canada

References

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Brown, F.D., Hanlon, K., Mullan, S. (1978). Treatment of aneurysmal hemiplegia with dopamine and mannitol. J. Neurosurg. 49: 525529.
Grubb, R.L., Raichle, M.E., Eichling, J.O. (1977). Effect of subarachnoid hemorrhage on cerebral blood volume, blood flow and oxygen utilization in humans. J. Neurosurg. 46: 446453.
Ishii, R. (1979). Regional cerebral blood flow in patients with ruptured intracranial aneurysms. J. Neurosurg. 50: 587594.
Kosnik, E.J., Hunt, W.E. (1976). Postoperative hypertension in the management of patients with intracranial arterial aneurysm. J. Neurosurg. 45: 148154.
Obrist, W.D., Thompson, H.K., Wang, H.S., Wilkinson, W.E. (1975). Regional cerebral blood flow estimated by 133 Xenon inhalation. Stroke 6: 245255.
Pritz, M.B., Gianotta, S.L., Kindt, G.W. (1978). Treatment of patients with neurological deficits associated with cerebral vasospasm by intravascular volume expansion. Neurosurgery 3: 364368.
Weir, B., Menon, D., Overton, T. (1978). Regional cerebral blood flow in patients with aneurysms: Estimation by Xenon 133 inhalation. Can. J. Neurol. Sci. 5: 301305.

Effect of Therapy on Cerebral Blood Flow Following Aneurysm Surgery

  • Bryce Weir (a1), Roberto Deleo (a1) and Devidas Menon (a1)

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