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CSF Electrophoresis: An Adaptation Using Cellulose Acetate for the Identification of Oligoclonal Banding

Published online by Cambridge University Press:  18 September 2015

D.W. Paty ,
M. Donnelly  and
M.E. Bernardo
D.W. Paty*
Affiliation:
Departments of Clinical Neurological Sciences, Instructional Resources and Clinical Biochemistry, University Hospital, University of Western Ontario, London, Ontario
M. Donnelly
Affiliation:
Departments of Clinical Neurological Sciences, Instructional Resources and Clinical Biochemistry, University Hospital, University of Western Ontario, London, Ontario
M.E. Bernardo
Affiliation:
Departments of Clinical Neurological Sciences, Instructional Resources and Clinical Biochemistry, University Hospital, University of Western Ontario, London, Ontario
*
Department of Clinical Neurological Sciences, University Hospital, P.O. Box 5339, H3A 2B4, Postal Station A., London, Ontario N6A 5A5, Canada.
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Summary:

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An adaptation of cellulose acetate electrophoresis for studying concentrated cerebrospinal fluid is described. Two hundred and twenty-one patients have been studied, and the specificity for multiple sclerosis and sub-acute sclerosing panencephalitis is discussed. This has been positive for oligoclonal banding (OB) in 79% of patients with clinically definite multiple sclerosis.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 5 , Issue 3 , August 1978 , pp. 297 - 299
Copyright
Copyright © Canadian Neurological Sciences Federation 1978

References

REFERENCES

Kabat, E., Landow, H., and Moore, D. (1942). Electrophoretic patterns of concentrated cerebrospinal fluid. Pro Soc Exp Biol Med. 49: 260–263.CrossRefGoogle Scholar
Link, H., and Muller, R. (1971). Immunoglobulins in multiple sclerosis and infections of the nervous system. Arch Neurol. 25: 326–344.CrossRefGoogle ScholarPubMed
Schumacher, G., Beebe, G., Kibler, R., Kurland, L., Kurtzke, J., Mcdowell, F., Nagler, B., Sibley, W., Tourtellotte, W., Willmon, T. (1965).Problems of experimental trials of therapy in multiple sclerosis: report by the panel on the evaluation of experimental trials of therapy in multiple sclerosis. Annals of N.Y. Academy of Sciences. 122: 552–568.CrossRefGoogle Scholar