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Creutzfeldt-Jakob Disease: Correlation of Focal Electroencephalographic Abnormalities and Clinical Signs

Published online by Cambridge University Press:  18 September 2015

Douglas E. Eggertson
Affiliation:
Section of Neurology, Department of Medicine, Health Sciences Centre and University of Manitoba, Winnipeg, Manitoba, Canada
Neelan Pillay
Affiliation:
Section of Neurology, Department of Medicine, Health Sciences Centre and University of Manitoba, Winnipeg, Manitoba, Canada
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Abstract:

Three patients are described with pathologically verified Creutzfeldt-Jakob disease (CJD) who presented with localizing clinical signs accompanied by focal electroencephalographic abnormalities including periodic lateralized epileptiform discharges (PLEDS). With further progression of the disease, diffuse background slowing and continuous bisynchronous periodic discharges appeared in all three cases. There was good correlation between the initial focal clinical manifestations and the EEG findings.

Type
Original Articles
Copyright
Copyright © Canadian Neurological Sciences Federation 1986

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