Hostname: page-component-848d4c4894-cjp7w Total loading time: 0 Render date: 2024-06-22T18:32:03.704Z Has data issue: false hasContentIssue false

Coexistence of Idiopathic Parkinson’s Disease and Creutzfeldt-Jakob Disease

Published online by Cambridge University Press:  18 September 2015

C. Ezrin-Waters
Affiliation:
Division of Neurology, Toronto Western Hospital
L. Resch
Affiliation:
Division of Neurology, Toronto Western Hospital
A.E. Lang*
Affiliation:
Division of Neurology, Toronto Western Hospital
*
Division of Neurology, Toronto Western Hospital, 399 Bathurst Street, Toronto, Ontario, Canada M5T 2S8
Rights & Permissions [Opens in a new window]

Abstract:

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The association of idiopathic Parkinson’s disease and Creutzfeldt-Jakob disease has not been reported previously. We describe the clinical findings in a patient with both disorders, confirmed at autopsy. The differential diagnosis of parkinsonism with cognitive and psychiatric disturbances is reviewed with emphasis on conditions which may complicate the course of idiopathic Parkinson’s disease. The etiological implications of this combination are considered.

Type
Original Articles
Copyright
Copyright © Canadian Neurological Sciences Federation 1985

References

REFERENCES

1.Hakim, AM, Mathieson, G.Dementia in Parkinson’s disease: A neuropathologic study. Neurology 1979; 29: 12091214.CrossRefGoogle ScholarPubMed
2.Jacobs, L, Conti, D, Kinkel, WR, et al. “Normal-pressure” hydrocephalus. Relationship of clinical and radiographic findings to improvement following shunt surgery. JAMA 1976; 235: 510512.CrossRefGoogle ScholarPubMed
3.Molsa, PK, Marttila, RJ, Rinne, UK.Extrapyramidal signs in Alzheimer’s disease. Neurology 1984; 34: 11141116.CrossRefGoogle ScholarPubMed
4.Sypert, CW, Leffman, H.Ojemann, GA.Occult normal pressure hydrocephalus manifested by Parkinsonism dementia complex. Neurology 1973;23:234238.CrossRefGoogle ScholarPubMed
5.Brown, P, Cathala, F, Sadowsky, D, et al. Creutzfeldt-Jakob disease in France: II. Clinical characteristics of 124 consecutive verified cases during the decade 1968–1977. Ann Neurol 1979; 6: 430437.CrossRefGoogle ScholarPubMed
6.Brown, P, Rodgers-Johnson, P, Cathala, Fet al. Creutzfeldt-Jakob disease of long duration: clinicopathological characteristics, transmissibility, and differential diagnosis. Ann Neurol 1984; 16: 295304.CrossRefGoogle ScholarPubMed
7.Gibbs, CJJr, Gadjusek, DC.Amyotrophic Lateral Sclerosis. Parkinson’s disease and the amyotrophic lateral sclerosis-Parkinsonism-dementia complex of Guam: A review and summary of attempts to demonstrate infection as the etiology. J Clin Path 1972; 25 (suppl 6): 132140.CrossRefGoogle Scholar