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The Association between Polycystic Kidney Disease and Cerebral Aneurysms

Published online by Cambridge University Press:  18 September 2015

Michael G. Fehlings  and
Fred Gentili
Michael G. Fehlings
Affiliation:
Division of Neurosurgery, The Toronto Hospital, Western Division and University of Toronto, Toronto
Fred Gentili*
Affiliation:
Division of Neurosurgery, The Toronto Hospital, Western Division and University of Toronto, Toronto
*
Division of Neurosurgery, The Toronto Hospital, Western Division, 399 Bathurst St, Toronto, Ontario, Canada M5T 2S8
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Abstract:

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Rupture of cerebral aneurysms is an important cause of morbidity and mortality in patients with adult polycystic kidney disease (PKD). In the present paper, we review the literature regarding the association of cerebral aneurysms and PKD and emphasize, by means of a case report, the importance of familial clustering of aneurysms in patients with PKD. We conclude that the prevalence of intracranial aneurysms in patients with PKD approaches 40% and is likely significantly higher in patients with PKD and a positive family history for cerebral aneurysm. We recommend that screening cerebral angiography be strongly considered in all patients with PKD and a family history of cerebral aneurysm or subarachnoid hemorrhage.

Type
Articles
Information
Canadian Journal of Neurological Sciences , Volume 18 , Issue 4 , November 1991 , pp. 505 - 509
Copyright
Copyright © Canadian Neurological Sciences Federation 1991

References

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